...Kishor K. Sivaraj; Ralf H. Adams In addition to their conventional role as a conduit system for gases, nutrients, waste products or cells, blood vessels in the skeletal system play active roles in controlling multiple aspects of bone formation and provide niches for hematopoietic stem cells...

...Alexandra M. Ochsenbein; Sinem Karaman; Steven T. Proulx; Michaela Berchtold; Giorgia Jurisic; Esther T. Stoeckli; Michael Detmar Vascular endothelial growth factor (VEGF)-A is a well-known major chemoattractant driver of angiogenesis – the formation of new blood vessels from pre-existing ones...

...-crest-derived vascular smooth muscle cells cooperate to control pharyngeal arch remodeling and are essential for heart and outflow tract septation. Aneurysms Blood vessels Cardiovascular development Integrin Neural crest Vascular smooth muscle cells Vascular smooth muscle cells (vSMCs...

... forms a web-like blood vessel network that penetrates the supportive epidermis of BTs. Upon analyzing the effects of sex steroids and their inhibitors, we show that androgens induce and estrogens inhibit BT cluster formation in intact and regenerating pectoral fins. Androgen-induced BT formation...

... Competing interests statement The authors declare no competing financial interests. 12 8 2013 © 2013. Published by The Company of Biologists Ltd 2013 Biomechanics Blood vessels Hemodynamics Low Reynolds number Zebrafish Embryonic blood flow is essential...

... their niche. Endogenous progenitor cell recruitment towards the lesion was significantly reduced by inhibiting post-lesional angiogenesis in the SVZ using anti-VEGF blocking antibody injections, suggesting a facilitating role of blood vessels for progenitor cell migration towards the lesion. We identified...

...Judith Magenheim; Ohad Ilovich; Alon Lazarus; Agnes Klochendler; Oren Ziv; Roni Werman; Ayat Hija; Ondine Cleaver; Eyal Mishani; Eli Keshet; Yuval Dor How organ size and form are controlled during development is a major question in biology. Blood vessels have been shown to be essential for early...

...Heloise West; William D. Richardson; Marcus Fruttiger Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes...

... of developing bones between wild-type and VEGF 120/120 mice. VEGF 120/120 mice have not only a delayed recruitment of blood vessels into the perichondrium but also show delayed invasion of vessels into the primary ossification center, demonstrating a significant role of VEGF at both an early and late stage...

... evidence that Bves is a novel cell adhesion molecule and suggests a role for Bves in coronary vasculogenesis. ‡Author for correspondence (e-mail: david.bader@mcmail.vanderbilt.edu ) 19 3 2001 © 2001. 2001 Heart Blood vessels Cell adhesion Chick Bves Generation...

... axons may be below the limit of detection with our antibody. Alternatively, the PDGF-A that is associated with RGC axons in the retina may be surfacebound, not intracellular. In the eye and optic nerve, the distribution pattern of PDGFB mRNA is very similar to that of PDGF-βR mRNA. Blood vessels...

... embryonic mesenchy- mal and epithelial tissues and participating in new blood vessel formation in distant sites. The interactions leading to proper spatial pattern- ing of craniofacial skeletal, muscular, vascular and peripheral neural tissues has been studied by perform- ing heterotopic transplants of each...