.... Arteriovenous malformation RASA1 Blood vessel MAPK Cumming School of Medicine, University of Calgary http://dx.doi.org/10.13039/100012866 Canadian Institutes of Health Research http://dx.doi.org/10.13039/501100000024 Heart and Stroke Foundation of Canada http://dx.doi.org...

...Elvin V. Leonard; Sana Safatul Hasan; Arndt F. Siekmann ABSTRACT Blood vessels form elaborate networks that depend on tissue-specific signalling pathways and anatomical structures to guide their growth. However, it is not clear which morphogenetic principles organize the stepwise assembly...

... showed a reduction in laminin protein expression in parenchymal basement membranes. Blood vessels in the Itga7 −/− brain showed separation from surrounding astrocytes and had reduced expression of the tight junction proteins claudin 5 and ZO-1. We propose that the alpha7 integrin subunit in astrocytes...

... promoter activity in this precursor lineage. Therefore, also in the zebrafish fin, Pdgfrb signalling is instrumental for proper mural cell specification. However, proximal blood vessel segments were still ensheathed with mural cells expressing transgenes driven by both pdgfrb and myh11a promoters...

...Ceilidh Marchant; Peter Anderson; Quenten Schwarz; Sophie Wiszniak ABSTRACT Craniofacial development is a complex morphogenic process that requires highly orchestrated interactions between multiple cell types. Blood vessel-derived angiocrine factors are known to promote proliferation...

...: Live imaging and genetic ablation experiments reveal the regulation of blood flow in early developing zebrafish cerebral vessels, and the role of pericytes and vascular smooth muscle cells in response to stimuli. Pericyte Vascular smooth muscle cell (vSMC) Blood vessel Vasomotor activity...

...-mouse IgG and Cy3-conjugated donkey anti-goat Fab fragment (Jackson ImmunoResearch). No staining was detected using the anti-NRP1 antibody in Nrp1 null tissue ( Fig. 2 A,B; Fig. 3 A,B; Figs S3 and S4 ). Blood vessels were detected using biotinylated IB4 (Sigma-Aldrich) followed by Alexa-Fluor633...

... and is mediated by the AP-1 transcription factor Fosl1. Auditory ossicle Blood vessel Synchrotron radiation AP-1 transcription factor Osteogenic capillary Angiogenesis and osteogenesis are closely linked during bone development, remodeling and regeneration ( Boerckel et al., 2011 ; Street et al...

... receptors. Thus,we propose a new model where blood vessel-derived sphingosine-1-phosphate stimulates growth and budding of the dorsal pancreatic endoderm by induction of mesenchymal cell proliferation. § Author for correspondence (e-mail: henrik.semb@endo.mas.lu.se ) * These authors contributed...

... vascular development: it is capable of initiating angiogenesis via promoting endothelial cell proliferation and chemoattraction, it maintains viability of immature blood vessels and it facilitates the process of pericyte recruitment. Its role in accelerating pericyte coverage is a novel function...