...Alexander Hirschhäuser; Darius Molitor; Gabriela Salinas; Jörg Großhans; Katja Rust; Sven Bogdan ABSTRACT Drosophila blood cells called hemocytes form an efficient barrier against infections and tissue damage. During metamorphosis, hemocytes undergo tremendous changes in their shape and behavior...

... embryo and discuss the role of flow of blood, lymph and cerebrospinal fluid in sculpting the embryonic cardiovascular and nervous system. Shear stress Blood Lymph Cerebrospinal fluid Cilia Mechanosensation Fonds Wetenschappelijk Onderzoek 10.13039/501100003130 11ZD516N G091018N...

...Seung-Hye Jung; Cory J. Evans; Christine Uemura; Utpal Banerjee Drosophila hematopoiesis occurs in a specialized organ called the lymph gland. In this systematic analysis of lymph gland structure and gene expression, we define the developmental steps in the maturation of blood cells(hemocytes) from...

...-of-function studies have shown that Lmo2 and Scl/Tal1 are essential for haematopoiesis and angiogenic remodelling of the vasculature, gain-of-function studies have suggested an earlier role for Scl/Tal1 in the specification of haemangioblasts, putative bipotential precursors of blood and endothelium...

...Anne Holz; Barbara Bossinger; Thomas Strasser; Wilfried Janning; Robert Klapper As in many other organisms, the blood of Drosophila consists of several types of hemocytes, which originate from the mesoderm. By lineage analyses of transplanted cells, we specified two separate anlagen that give rise...

...Maggie Walmsley; Aldo Ciau-Uitz; Roger Patient Blood and blood vessels develop in close association in vertebrate embryos and loss-of-function mutations suggest common genetic regulation. By the criteria of co-expression of blood and endothelial genes, and lineage tracing of progeny, we locate two...

... blood island (VBI), are specified at the ventral pole. We report here that the genes Xvent-1, Xvent-2 , and Xwnt-8 do not appear to be in the pathway of VBI induction, contrary to previous reports. Results from the selective inhibition of bone morphogenetic protein (BMP) activity, a key regulator of VBI...

...Leon Parker; Didier Y. R. Stainier ABSTRACT Vertebrate embryonic hematopoiesis is a complex process that involves a number of cellular interactions, notably those occurring between endothelial and blood cells. The zebrafish cloche mutation affects both the hematopoietic and endothelial lineages...

...Mary Constance Lane; William C. Smith ABSTRACT The marginal zone in Xenopus laevis is proposed to be patterned with dorsal mesoderm situated near the upper blastoporal lip and ventral mesoderm near the lower blastoporal lip. We determined the origins of the ventralmost mesoderm, primitive blood...

... of Technology, Pasadena, California, 91125, USA (e-mail: [email protected] ) 06 03 1997 © 1997 by Company of Biologists 1997 hematopoietic stem cell lineage transplantation selfrenewal bone marrow blood stem cell The bone marrow multipotent progenitor pool must...

... Nüsslein-Volhard ABSTRACT As part of a large scale chemical mutagenesis screen of the zebrafish ( Danio rerio ) genome, we have identified 33 mutants with defects in hematopoiesis. Complementation analysis placed 32 of these mutants into 17 complementation groups. The allelism of the remaining 1 blood...