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Keywords: Bivalent promoters
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Journal Articles
Sergei Denissov, Helmut Hofemeister, Hendrik Marks, Andrea Kranz, Giovanni Ciotta, Sukhdeep Singh, Konstantinos Anastassiadis, Hendrik G. Stunnenberg, A. Francis Stewart
Journal:
Development
Development (2014) 141 (3): 526–537.
Published: 1 February 2014
... and a key product of Trithorax group action. Here, we show that Mll2, one of the six Set1/Trithorax-type H3K4 methyltransferases in mammals, is required for trimethylation of bivalent promoters in mouse embryonic stem cells. Mll2 is bound to bivalent promoters but also to most active promoters, which do...
Includes: Supplementary data
