...Nikolay Postika; Paul Schedl; Pavel Georgiev; Olga Kyrchanova ABSTRACT The Abdominal-B ( Abd-B ) gene belongs to the bithorax complex and its expression is controlled by four regulatory domains, iab-5 , iab-6 , iab-7 and iab-8 , each of which is thought to be responsible for directing...

...Carole Iampietro; Fabienne Cléard; Henrik Gyurkovics; Robert K. Maeda; François Karch Although the boundary elements of the Drosophila Bithorax complex(BX-C) have properties similar to chromatin insulators, genetic substitution experiments have demonstrated that these elements do more than simply...

.... Promoter competition and insulators are thought to play a role in regulating these interactions. In the bithorax complex of Drosophila , the IAB5 enhancer is located 55 kb 3′ of the Abdominal-B ( Abd-B ) promoter and 48 kb 5′ of the abdominal-A ( abd-A ) promoter. Although roughly equidistant from the two...

...Jozsef Mihaly; Stéphane Barges; Laszlo Sipos; Robert Maeda; Fabienne Cléard; Ilham Hogga; Welcome Bender; Henrik Gyurkovics; François Karch The three homeotic genes of the bithorax complex (BX-C), Ubx,abd-A and Abd-B control the identity of the posterior thorax and all abdominal segments. Large...

...Susan E. Schweinsberg; Paul Schedl The Fab-7 boundary functions to ensure the autonomous activity of the iab-6 and iab-7 cis-regulatory domains in the Drosophila Bithorax Complex from early embryogenesis through to the adult stage. Although Fab-7 is required only for the proper development...

...Welcome Bender; Daniel P. Fitzgerald A series of mutations have been recovered in the bithorax complex of D. melanogaster that transform the first segment of the abdomen into a copy of the second or third abdominal segment. These dominant Ultraabdominal alleles are all associated with P element...

...Welcome Bender; Andrew Hudson ABSTRACT P elements containing a 7 kb DNA fragment from the middle of the Drosophila bithorax complex insert preferentially into the bithorax complex or into the adjacent chromosome regions. This ‘homing’ property is similar to that reported for the engrailed promoter...