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Keywords: Bistability
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Journal Articles
Journal:
Development
Development (2021) 148 (24): dev199779.
Published: 22 December 2021
... cell-fate transitions, yet models rarely take this into account. Here, we have developed a multiscale perspective to study the granulocyte-monocyte versus megakaryocyte-erythrocyte fate decisions. This transition is dictated by the GATA1-PU.1 network: a classical example of a bistable cell-fate system...
Includes: Supplementary data
