... in cell morphology in the auditory sensory epithelium. This study reveals a fundamental mechanism regulating cell morphology and frequency-place coding in the developing cochlea. Metabolism Mitofusin Biogenesis Hearing Chick Biotechnology and Biological Sciences Research Council http...

... indicates that the complexity and diversity of ribosome biogenesis and function should be given a fresh look in the context of development. This Review begins with a discussion of different developmental disorders that have been linked with perturbations in ribosome production and function. We...

... evolution, reactions such as miRNA processing have to be adjusted to fluctuating environmental temperatures. Here, we report that with decreasing ambient temperature, the plant miRNA biogenesis machinery becomes more robust, producing miRNAs even in the absence of the key DCL1 co-factors HYL1 and SE...

...João Ferreira; Maria Carmo-Fonseca ABSTRACT The coiled body is an ubiquitous nuclear organelle that contains essential components of the pre-mRNA splicing machinery as well as the nucleolar protein fibrillarin. Here we have studied the biogenesis of the coiled body in early mouse embryos...