... Cdc42 Par6 Par3 Bazooka aPKC Crumbs Par complex Medical Research Council MC_UU_12018/3 MC_UU_00012/3 Epithelial cell polarity and morphogenesis involve the specification and maturation of distinct plasma membrane domains along the apical (top) to basal (bottom) axis...

... transition (MET). FGF activity leads to accumulation of β-integrin Myospheroid basally and cell polarity factor Bazooka apically within mesoderm cells, thereby reestablishing apicobasal cell polarity in an epithelialized state in which cells express both E-Cadherin and N-Cadherin. In summary, FGF plays...

...Andrea Leibfried; Sandra Müller; Anne Ephrussi Polarity of the Drosophila oocyte is essential for correct development of the egg and future embryo. The Par proteins Par-6, aPKC and Bazooka are needed to maintain oocyte polarity and localize to specific domains early in oocyte development. To date...

... by polarized embryonic cell movements . Science 298 , 1950 – 1954 . Krahn M. P. , Klopfenstein D. R. , Fischer N. , Wodarz A. ( 2010 ). Membrane targeting of Bazooka/PAR-3 is mediated by direct binding to phosphoinositide lipids . Curr. Biol. 20 , 636 – 642...

... and maintaining epithelial cell polarity. However,less is known about what becomes of epithelial polarity proteins when various cell types become migratory and invasive. Here, we report the localization of several apical epithelial proteins, Par-6, Par-3/Bazooka and aPKC, during border cell migration...

...Salim Abdelilah-Seyfried; Daniel N. Cox; Yuh Nung Jan Drosophila Bazooka and atypical protein kinase C are essential for epithelial polarity and adhesion. We show here that wild-type bazooka function is required during cell invasion of epithelial follicle cells mutant for the tumor suppressor discs...