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Keywords: Basic helix-loop-helix
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Journal Articles
Journal: Development
Development (2015) 142 (16): 2810–2821.
Published: 15 August 2015
...Israt Jahan; Ning Pan; Jennifer Kersigo; Bernd Fritzsch Atoh1 , a basic helix-loop-helix (bHLH) transcription factor (TF), is essential for the differentiation of hair cells (HCs), mechanotransducers that convert sound into auditory signals in the mammalian organ of Corti (OC). Previous work...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (23): 4691–4702.
Published: 1 December 2013
..., planarians provide a powerful model to identify genes required for adult neurogenesis in vivo . We analyzed the basic helix-loop-helix (bHLH) family of transcription factors, many of which are crucial for nervous system development and have been implicated in human diseases. However, their potential roles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4439–4450.
Published: 15 November 2006
... and one class of glial cells, all derived from a population of multipotent progenitors. There is little information on the molecular mechanisms governing the specification of cell type identity from multipotent progenitors in the developing retina. We report that Ptf1a, a basic-helix-loop-helix (bHLH...
Journal Articles
Journal: Development
Development (2005) 132 (17): 3907–3921.
Published: 1 September 2005
... Retina patterning Basic helix-loop-helix Transcription Chick embryo The early development of the vertebrate central nervous system crucially depends on the timely generation of specific classes of neurons at distinct positions and in appropriate numbers. A large set of different regulatory...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (18): 4447–4454.
Published: 15 September 2004
...Dorota Skowronska-Krawczyk; Marc Ballivet; Brian D. Dynlacht; Jean-Marc Matter Basic helix-loop-helix (bHLH) transcription factors such as atonal homolog 5 (ATH5) and neurogenin 2 (NGN2) determine crucial events in retinogenesis. Using chromatin immunoprecipitation, we demonstrate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (13): 3077–3088.
Published: 1 July 2002
...David G. McFadden; John McAnally; James A. Richardson; Jeroen Charité; Eric N. Olson Basic helix-loop-helix (bHLH) transcription factors control developmental decisions in a wide range of embryonic cell types. The HLH motif mediates homo- and heterodimerization, which juxtaposes the basic regions...
Journal Articles
Journal: Development
Development (2002) 129 (10): 2459–2472.
Published: 15 May 2002
... of the homeobox proteins Pax6, Dbx2 and Msx1 generates precursor populations with distinct developmental potentials. Within the resulting populations, thresholds of BMP act to set expression domain boundaries of developmental regulators of the homeobox and basic helix-loop-helix (bHLH) families, ultimately...