...Yingqian Xia; Yizhi Zhang; Min Xu; Xiaochuan Zou; Jun Gao; Mu-Huo Ji; Guiquan Chen ABSTRACT Recent evidence has shown that presenilin enhancer 2 (Pen2; Psenen) plays an essential role in corticogenesis by regulating the switch of apical progenitors (APs) to basal progenitors (BPs). The hippocampus...

...Zhili Hou; Qi Wu; Xin Sun; Huaiyong Chen; Yu Li; Yongchun Zhang; Munemasa Mori; Ying Yang; Jianwen Que; Ming Jiang ABSTRACT Basal progenitor cells are crucial for the establishment and maintenance of the tracheal epithelium. However, it remains unclear how these progenitor cells are specified...

... present in various vertebrate species. For example, in both mammals and birds, proliferative neuronal progenitors transiently appear on the basal side of the ventricular zone of the telencephalon (basal progenitors), where they contribute to the enlargement of the neocortex and its homologous structures...

... Tbr2, and eventually delaminate from the apical adherens junction belt to become basal progenitors, translocating their nucleus from the ventricular to the subventricular zone. Overexpression of insulinoma-associated 1, a transcription factor known to promote the generation of basal progenitors...