...) * Present address: Nara Institute of Science and Technology, Ikoma 630-0101,Japan 9 9 2004 © 2004. 2004 Adherens junction Basal lamina bHLH Neuroepithelium Radial glia Tight junction Organogenesis involves the initial proliferation process of stem cells and the subsequent...

... a defect in the apical ectodermal ridge, an essential limb organizing center. In the double mutant, the ridge appeared flattened, and ridge cells did not show a columnar morphology. A strong reduction in ridge cell proliferation and alterations of the basal lamina underlying the ectoderm were observed...

... mesenchyme cell organization and endoderm morphogenesis during gastrulation. Second, during gastrulation, ECM 18 mRNA accumulates to highest levels in the invaginating endoderm and the ECM 18 protein is deposited in the basal lamina surrounding the archenteron as well as in other areas of the blastocoel wall...

... to myelination demonstrated that Schwann cells must form a basal lamina in order to myelinate an axon. In this report, we describe studies that indicate that initiation of basal lamina synthesis is required for Schwann cells to distinguish between myelination-inducing axons and axons that do not induce...

... with the basal lamina/extracellular matrix that are non-uniformly distributed along the proximal-distal axis of cockroach legs at the time of pioneer axon growth. Two of these mAbs, PROD-1 and PROD-2, label the proximal parts of the leg more intensely than the distal ends. The other mAb, DIP-1, has the reverse...

...H. R. Brenner; A. Herczeg; C. R. Slater ABSTRACT To test the hypothesis that synaptic basal lamina can induce synapse-specific expression of acetylcholine receptor (AChR) genes, we examined the levels mRNA for the and -subunits of the AChR in regenerating rat soleus muscles up to 17 days...

... deposition of the junctional basal lamina. Using cultured nerve and muscle cells from anuran and urodele embryos, we prepared species-chimaeric synapses that displayed spontaneous cholinergic potentials, and eventually developed organized accumulations of acetylcholine receptors and HSPG at the sites...

...Willi Halfter ABSTRACT In order to determine the role of the extracellular matrix in regulating the directed growth of embryonic neurites, antisera to retina (a-RBL I and II), to pigment epithelium (a-PBL) and to glomerular (a-GBL) basal lamina were probed for an effect on the ordered extension...

...Hilary Anderson; Richard P. Tucker The pioneer neurones of the embryonic grasshopper limb use the basal lamina underlying the limb ectoderm as a substratum over which to grow from the periphery to the CNS (Anderson & Tucker, 1988). In this paper we use transmission electron microscopy...

... frequent contacts with basal lamina underlying the ectoderm. Components of the basal lamina may therefore play a role in guiding pioneer axon outgrowth. Here we address this question in a simple system, the peripheral nervous system of the grasshopper embryo. At 30% of embryonic development, the limb...

... surface of the lateral extremes of the neural plate. Nevertheless, the two epithelia remain connected across the zone of delamination by their previously existing basal laminae. In each fold, proteoglycan granules appear at the interface between the NE and EE before delamination begins, and then an (inter...

...M. Martins-Green; C. A. Erickson ABSTRACT One of the factors proposed to control initiation of migration of neural crest (NC) cells is disruption of the basal lamina (BL) that is presumed to exist over the dorsal portion of the neural tube. Previously, we discovered that, in the mouse embryo...

... postulated to be important in the initiation of migration of NC cells is the disruption of the basal lamina (BL) over the dorsal portion of the neural tube. It has been assumed by many that the BL must be discontinuous in order that the NC cells can leave the neural tube; and indeed, experiments performed...

...Betty C. Gallagher ABSTRACT The developing chick lung was examined in the electron microscope for intimate cell contacts between epithelium and mesenchyme, discontinuities in the basal lamina and substructure of the basement membrane. Cell filopodia were seen which crossed the basal lamina from...

... the epidermis and on its surface. Among these cells are nerve fibres and Schwann cells as well as other unidentified cells. Antibodies directed against fibronectin bind to these abnormal groups of cells in the mutant epidermis and on its surface. A basal lamina, as determined by ultrastructure and by the immuno...