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Keywords: Bam
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Journal Articles
Journal: Development
Development (2020) 147 (2): dev182063.
Published: 15 January 2020
... . 10.1038/sj.onc.1203706 Chen , D. and McKearin , D. M. ( 2003 ). A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell . Development   130 , 1159 - 1170 . 10.1242/dev.00325 Chen , G. , Kong , J. , Tucker...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (13): 2261–2267.
Published: 1 July 2015
...Tsuyoshi Tokusumi; Yumiko Tokusumi; Dawn W. Hopkins; Robert A. Schulz Bag of Marbles (Bam) is known to function as a positive regulator of hematopoietic progenitor maintenance in the lymph gland blood cell-forming organ during Drosophila hematopoiesis. Here, we demonstrate a key function for Bam...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (18): 3879–3884.
Published: 15 September 2011
...Tsuyoshi Tokusumi; Yumiko Tokusumi; Dawn W. Hopkins; Douglas A. Shoue; Lauren Corona; Robert A. Schulz Bag of Marbles (Bam) is a stem cell differentiation factor in the Drosophila germ line. Here, we demonstrate that Bam has a crucial function in the lymph gland, the tissue that orchestrates...
Journal Articles
Journal: Development
Development (2005) 132 (6): 1165–1174.
Published: 15 March 2005
... that Twin controls germ line cyst development by regulating poly(A) tail lengths of several targets including Cyclin A ( CycA ) RNA. twin mutants exhibit very low expression of Bag-of-marbles (Bam), a regulator of cyst division, indicating that Twin/Ccr4 activity is necessary for wild-type Bam expression...
Journal Articles
Journal: Development
Development (2004) 131 (9): 1881–1890.
Published: 1 May 2004
... that gives rise to both a GSC,which remains associated with the CpCs, and a more posterior located cystoblast (CB). The CB upregulates expression of the novel gene, bag of marbles ( bam ), which is necessary for germline differentiation. Decapentaplegic (Dpp), a BMP2/4 homologue, has been postulated to act...
Journal Articles
Journal: Development
Development (2004) 131 (6): 1365–1375.
Published: 15 March 2004
... act on GSCs and control their maintenance. In GSCs defective in Bmp signaling,expression of bam is upregulated, whereas forced bam expression in GSCs causes the GSCs to be lost. This study demonstrates that Bmp signals from the somatic cells maintain GSCs, at least in part, by repressing bam...
Journal Articles
Journal: Development
Development (1997) 124 (21): 4361–4371.
Published: 1 November 1997
... that embark on the differentiation program specific for the given lineage. Spermatogenesis in Drosophila is a model system to identify molecules regulating stem cell lineages. Mutations at two previously identified loci, bag-of-marbles ( bam ) and benign gonial cell neoplasm ( bgcn ), prevent progression...
Journal Articles
Journal: Development
Development (1997) 124 (18): 3651–3662.
Published: 15 September 1997
...Benjamin Ohlstein; Dennis McKearin ABSTRACT The Drosophila germ-cell lineage has emerged as a remark-able system for identifying genes required for changes in cell fate from stem cells into more specialized cells. Previous work indicates that bam expression is necessary for cystoblast...