... the abundance of bHLH factors to optimize photomorphogenesis in Arabidopsis . bHLH transcription factor E3 ubiquitin ligase Photomorphogenesis Reciprocal degradation 26S proteasome National Institutes of Health 10.13039/100000002 1R01 GM-114297 National Science Foundation...

... the GA pathway and is necessary for promoting flowering in Arabidopsis under non-inductive short-day conditions. Arabidopsis BHLH transcription factor Flowering time GA signaling pathway Photoperiod pathway Flowering is a transition from the vegetative to reproductive phase...

... and musculoskeleton of the trunk and tail. The Wnt-regulated basic helix-loop-helix (bHLH) transcription factor mesogenin 1 (Msgn1) has been implicated as a cooperative regulator working in concert with T-box genes to control PSM formation in zebrafish, although the mechanism is unknown. We show here that, in mice...

... by The Company of Biologists Ltd 2014 ChIP-Seq bHLH transcription factor Dorsal neural tube Neuronal subtype specification Mouse Chick Ascl1 Ptf1a The neurons within the dorsal spinal cord provide the initial integration for somatosensory information originating from the periphery...

... understood. Nato3 (also known as Ferd3l ) is an evolutionarily conserved basic helix-loop-helix (bHLH) transcription factor that is dynamically expressed in the embryonic and adult nervous system ( Mansour et al., 2011 ; Segev et al., 2001 ). In the developing neural tube, Nato3 expression...

... Neurog2 as the first neural target of Ptf1a and revealing a bHLH transcription factor cascade functioning in the specification of GABAergic neurons in the dorsal spinal cord and cerebellum. † Author for correspondence( [email protected] ) * These authors contributed equally...

... into understanding the machinery of neuron subtype specification in the dorsal hindbrain. * Author for correspondence (e-mail: [email protected] ) 16 4 2009 © 2009. 2009 Hindbrain Math1 bHLH transcription factor Cochlear nucleus Inhibitory Excitatory Mouse Sounds received...

... ) 3 4 2007 © 2007. 2007 Autonomic nervous system bHLH transcription factor Conditional knockout Enteric nervous system Gene knockout Gut development Mouse Basic helix-loop-helix (bHLH) transcription factors play important roles in lineage determination and differentiation...

... capacity to undergo neuronal differentiation, with a subset of these cells retaining characteristics of immature glial cells. * Author for correspondence (e-mail: [email protected] ) 2 11 2006 © 2007. 2007 Mash1 (Ascl1) bHLH transcription factor Spinal cord...

.... 2006 bHLH transcription factor GABAergic neurons Gad65 (Gad2) Gad67 (Gad1) Megane (Heslike, Helt ) Superior colliculus Midbrain Specification Mouse The GABAergic neurons are the principal inhibitory neurotransmitter system in the mammalian central nervous system (CNS...

.... The mutant meiocytes are able to complete meiosis I,but they do not have a thick callose wall; they often fail to complete meiotic cytokinesis and eventually collapse. DYT1 encodes a putative bHLH transcription factor and is strongly expressed in the tapetum from late anther stage 5 to early stage 6...

...) are associated with the loss of inhibitory activity of GABAergic neurons ( Ibuki et al.,1997 ; Wiesenfeld-Hallin et al., 1997 ). We demonstrate the requirement of the bHLH transcription factor, Ptf1a, for the overwhelming majority of GABAergic neurons present in the dorsal spinal cord. GABAergic...

...Elise Cau; Stephen W. Wilson The homeodomain transcription factor Floating head (Flh ) is required for the generation of neurones in the zebrafish epiphysis. It regulates expression of two basic helix loop helix (bHLH) transcription factor encoding genes, ash1a (achaete/scute homologue 1a...

... . Development 127 , 3373 – 3383 . 10.1242/dev.127.15.3373 Cell fate determination Notch signaling bHLH transcription factor Hes Math1 Cochlea Utricle Hair cell development Hair cell regeneration The bony labyrinth of the inner ear develops from the otic vesicle ( Van de Water...

... to associate with E12 ( Fig. 3B , lanes 12, 13), and cannot bind DNA ( Fig. 3A , lane 20). * Author for correspondence (e-mail: [email protected]) 11 08 1999 © 1999 by Company of Biologists 1999 SCL/tal-1 bHLH transcription factor Hematopoiesis Vasculogenesis...

...-mail: [email protected] ) 6 April 1999 18 February 1999 © 1999 by Company of Biologists 1999 MyoD bHLH Transcription factor Myogenesis Mouse Transgenic mouse Skeletal muscle of the vertebrate body is derived from somites, paired epithelial structures formed...

... specifically to dorsal commissural interneurons. * Author for correspondence (e-mail: [email protected]) 11 12 1997 © 1995 by Company of Biologists 1995 bHLH transcription factor Mouse Spinal cord MATH1 Neuron Cerebellum Neural tube During the development...