... provided evidence for sequential arborization of nociceptive and touch neuron axons in the CNS. We propose that axon–axon interactions and modality-specific timing of axon targeting play key roles in subcellular connection specificity of somatosensory circuitry. We next tested the role of axon...

... and post-migrating NM cells. FMRP downregulation induced by CRISPR/Cas9 and shRNA techniques resulted in perturbed axonal pathfinding, delay in midline crossing, excess branching of neurites, and axonal targeting errors during the period of circuit development. Together, these results provide the first...

...://www.biologists.com/user-licence-1-1/ Summary: A novel genetic strategy allowing the tracing of axonal projections in mouse brain identifies Rorβ as a key factor regulating axonal targeting to distinct subcortical areas. Rorβ Axon targeting Midbrain Superior colliculus Thalamus FLP-DOG...

... sensory neurons. Dendrite Drosophila Transcription factor Homeodomain POU domain Neuronal morphogenesis Axon targeting Fig. 8. Cut, Pdm1/2, Sd and Vg interact to diversify sensory neuron morphology. (A) Summary of the proposed regulatory interactions between Cut, Pdm1/2, Sd...

.... Drosophila Axon targeting Photoreceptor Sequences of genetically programmed developmental decisions play an important role in determining the complex architecture of the adult brain. At the level of single neurons, these decisions produce cellular morphologies that are characteristic of each...

... and Cellular Biophysics, Center for Neurobiology and Behavior, Columbia University, 630 W. 168th Street,P&S 11-451, New York, NY 10032, USA 28 9 2006 © 2007. 2007 Drosophila Sensory map Dendritic arborization neurons Genetic screen Axon targeting Dendrite morphogenesis...

... ) 25 11 2003 © 2004. 2004 Olfactory Axon targeting Transcription factor The sensory neurons of the mammalian olfactory system are remarkable in their ability to undergo continuous replacement throughout the lifespan of the animal ( Mackay-Sim and Kittel,1991 ). This continual...

.... In the larval and adult brain, Acj6 is highly expressed in central brain, optic and antennal lobe neurons. Loss of Acj6 function in larval optic lobe neurons results in disorganized retinal axon targeting and synapse selection. Furthermore, the lamina neurons themselves exhibit disorganized synaptic arbors...

... ). axon targeting chemotropism collateral branching corticospinal axons growth cones target recognition Copyright © 1991 by Company of Biologists 1991 ...