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Keywords: Axon outgrowth
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (20): dev193805.
Published: 26 October 2020
...Tessa Sherry; Ava Handley; Hannah R. Nicholas; Roger Pocock ABSTRACT Brain development requires precise regulation of axon outgrowth, guidance and termination by multiple signaling and adhesion molecules. How the expression of these neurodevelopmental regulators is transcriptionally controlled...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (16): dev191312.
Published: 27 August 2020
... interneurons. In the differentiation of V2a and V2b cells, Notch signaling promotes V2b fate at the expense of V2a fate. Later, V2b cells extend axons along the ipsilateral side of the spinal cord and express the inhibitory transmitter GABA. Notch signaling has been reported to inhibit the axonal outgrowth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (12): 2088–2093.
Published: 15 June 2015
... by The Company of Biologists Ltd 2015 Summary: This short review and accompanying poster highlight recent advances in our understanding of the molecular mechanisms underlying axon and dendrite specification in vitro and in vivo . Neuronal polarity Cellular asymmetry Axon outgrowth Dendrite...
Journal Articles
Journal: Development
Development (2013) 140 (2): 333–342.
Published: 15 January 2013
... complement of the Bmpr complex, to ensure the specific regulation of axon outgrowth rate by BMPs? Or is the activation of Limk1 non-specific, such that Limk1 is constitutively activated in the cytosol after dissociating from BmprII? Here, we provide evidence for the former model by showing that BmprIb...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (24): 4591–4600.
Published: 15 December 2012
... subpopulations have stereotypic cell body positions and show specific spatial axon trajectories. Our knowledge of MN axon outgrowth remains incomplete. Here, we report a zebrafish gene-trap mutant, short lightning ( slg ), in which prdm14 expression is disrupted. slg mutant embryos show shortened axons in caudal...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (13): 2392–2404.
Published: 1 July 2012
.... 18 4 2012 © 2012. Neuromuscular junction β-Catenin AChR Axon outgrowth Retrograde signals Mouse The neuromuscular junction (NMJ), a synapse between motoneurons and muscle fibers, is crucial for control of muscle contraction. This classic chemical synapse has...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5257–5267.
Published: 1 December 2011
... in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms. FOXO PTEN Axon outgrowth Dendrite morphology Neurodevelopment The phosphatidylinositol 3-kinase (PI3K...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (6): 911–922.
Published: 15 March 2009
... 2009. 2009 UNC-40 UNC-73 WAVE Dcc Trio GEX-2 GEX-3 UNC-95 Muscle arms Axon outgrowth Caenorhabditis elegans The postsynaptic membrane is not a passive partner in the development of the neuromuscular junction (NMJ). For example, the striated muscles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (21): 5233–5242.
Published: 1 November 2004
... demonstrates that Nkx6 acts in a specific neuronal population to link neuronal subtype identity to neuronal morphology and connectivity. The preceding analysis indicates that Nkx6 promotes axon outgrowth of a subset of MNs. To investigate this possibility in more detail, we followed the well...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (9): 1891–1902.
Published: 1 May 1999
... sensory axon morphology in C. elegans . A class of mutants with deformed sensory cilia at their dendrite endings have extra axon branches, suggesting that sensory deprivation disrupts axon outgrowth. Mutations that alter calcium channels or membrane potential cause similar defects. Cell-specific...
Journal Articles
Journal: Development
Development (1997) 124 (24): 5063–5074.
Published: 15 December 1997
... of these target tissues in vitro. Furthermore, the growth of corticofugal axons is oriented toward an ectopic source of netrin-1 in vitro, and a function blocking anti-netrin-1 antiserum specifically abolishes the cortical axon outgrowth elicited by explants of lateral GE and the ISS in collagen gel cocultures...
Journal Articles
Journal Articles
Journal: Development
Development (1993) 118 (2): 509–522.
Published: 1 June 1993
... restricted to a subset of axons later in development. This expression is unique among known insect neurogenic genes and suggests a role for Lachesin in early neuronal differentiation and axon outgrowth. Grasshopper Lachesin is a 38×10 3 M r protein linked to cell membranes through a glycosyl...
Journal Articles
Journal: Development
Development (1992) 116 (Supplement): 99–104.
Published: 1 April 1992
... 1992 by Company of Biologists 1992 neural cell adhesion molecule regulation of cell interactions adhesive preferences axon outgrowth Being the first cell adhesion molecule to be identified in vertebrate embryos, NCAM tended to be considered as a candidate receptor in nearly every...
Journal Articles