1-20 of 145
Keywords: Axon guidance
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2021) 148 (22): dev199584.
Published: 15 November 2021
... topographic sorting errors . Neuron 78 , 49 - 56 . 10.1016/j.neuron.2013.02.005 Poulain , F. E. , Gaynes , J. A. , Stacher Hörndli , C. , Law , M. Y. and Chien , C. B. ( 2010 ). Analyzing retinal axon guidance in zebrafish . Methods Cell Biol. 100 , 3 - 26 . 10.1016...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev199706.
Published: 14 September 2021
.... Genetically identifying the molecular determinants of target-specific axon guidance, and the cells in which they are expressed, will be important to distinguish between the possible mechanisms discussed here, and will constitute important future work in this system. Target specificity requires molecular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev199717.
Published: 30 July 2021
.... and Bargmann , C. I. ( 2006 ). MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin . Curr. Biol. 16 , 854 - 862 . 10.1016/j.cub.2006.03.083 Chen , B. , Legant , W. , Wang , K. , Shao , L. , Milkie , D. , Davidson , M...
Journal Articles
Journal: Development
Development (2021) 148 (12): dev191122.
Published: 15 June 2021
... factors play an integral role in the synaptic specificity of monosynaptic sensory-motor connections in the developing spinal cord. Axon guidance Motor neuron Proprioceptive sensory neuron Sensory-motor circuit Spinal cord Synaptic specificity Mouse To determine whether HoxD...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (20): dev196055.
Published: 29 October 2020
... is sufficient to repel axons. However, longitudinal axon guidance is highly disrupted in tok mutants and can be rescued by midline expression of Slit-N, suggesting that Slit is the primary substrate for Tok in the embryonic CNS. Transgenic restoration of Slit-N or Slit-C does not repel axons in Slit-null flies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (20): dev193805.
Published: 26 October 2020
.... Loss of CTBP-1 causes multiple defects in SMD axon development: premature outgrowth, defective guidance, delayed termination and absence of retraction. CTBP-1 controls SMD axon guidance by repressing the expression of SAX-7, an L1 cell adhesion molecule (L1CAM). CTBP-1-regulated repression is crucial...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (15): dev190637.
Published: 7 August 2020
... , the Caenorhabditis elegans homologue of the H3K4 methyltransferase KMT2F/G (SETD1A/B) genes, controls embryonic transcription of neuronal genes and is required for establishing proper axon guidance, and for neuronal functions related to locomotion and learning. Moreover, we uncover a striking correlation between...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (12): dev184523.
Published: 26 June 2020
... fasciculation. Thalamocortical tract Axon guidance Diencephalon Pax6 Thalamus Prethalamic pioneer axons A striking feature of the axonal tracts that interlink the component parts of the nervous system is the high degree of order with which they map the array of neurons in one structure onto...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (21): dev176461.
Published: 5 November 2019
... for neuroendocrine neurons to migrate into the hypothalamus and release gonadotropins into the circulation. GnRH neuron Olfactory bulb Testes Axon guidance Plexin Semaphorin Hypogonadotropic hypogonadism Kallmann syndrome GnRH-secreting neurons are hypothalamic neuroendocrine cells that regulate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (17): dev178103.
Published: 9 September 2019
... deduced features in subpopulations of RGCs allowed us to define novel molecular markers that are spatially restricted. Finally, the isolation of such a spatially restricted population, ipsilateral RGCs, allowed us to identify their molecular identity at the time they execute axon guidance decisions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (4): dev170704.
Published: 18 February 2019
... stereopsis. Although domain-specific axon guidance cues that discriminate contralateral and ipsilateral RGC axons have long been postulated as a key mechanism for development of the eye-specific retinogeniculate projection, the molecular nature of such cues has remained elusive. Here, we show...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (3): dev172106.
Published: 4 February 2019
...-licence-1-1/ Highlighted Article: At the ventral midline, developing commissural axons increase Slit sensitivity through a positive-feedback mechanism that is Arf6 mediated and driven by Robo1 receptor endocytic recycling. Slit-Robo Axon guidance Commissural neurons Midline Endocytic...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev168948.
Published: 16 January 2019
... ). Entactin, a novel basal lamina-associated sulfated glycoprotein . J. Biol. Chem.   256 , 5209 - 5214 . Chiang , C. , Patel , N. H. , Young , K. E. and Beachy , P. A. ( 1994 ). The novel homeodomain gene buttonless specifies differentiation and axonal guidance functions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (21): dev162552.
Published: 2 November 2018
... precursors into the adrenal primordia, ensuring correct regulation of the autonomic stress response. Adrenal gland Autonomic nervous system Axon guidance Chromaffin cell Neural crest cell Neuropilin Neuroendocrine chromaffin cells of the adrenal medulla produce adrenaline and noradrenaline...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (19): dev153692.
Published: 2 October 2018
... and in vivo observations indicate that Trio is a master integrator for factors that guide axonal growth and cell migration, and coordinate telencephalic wiring. Trio GEF RhoA Neuron Migration Slit2 Axon guidance Rho GTPase Mouse Embryo Thalamocortical Corridor cells The small...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (18): dev164897.
Published: 21 September 2018
..., EGL-20, through a mechanism that appears to be independent of canonical Fz-type receptors. Our results suggest that RPM-1 and the DLK-1 pathway regulate axon guidance and growth by preventing Wnt signaling crosstalk. * Author for correspondence ( rongo@waksman.rutgers.edu ) Competing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (12): dev159012.
Published: 14 June 2018
..., and that VANGL2 acts non-autonomously from the cochlea to direct turning. Moreover, VANGL2 is asymmetrically distributed at intercellular junctions between cochlear supporting cells, and in a pattern that could allow it to act directly as an axon guidance cue. Together, these data reveal a non-autonomous function...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (10): dev151415.
Published: 14 May 2018
... these axon guidance mechanisms, highlighting the most recent advances in the field that challenge the textbook model of axon guidance. Box 1. The role of the long-range chemoattractant netrin revisited The role of netrin as a guidance cue for commissural axons extending towards the floor plate...
Journal Articles
Journal: Development
Development (2018) 145 (3): dev160093.
Published: 8 February 2018
... Highlighted Article: The mutation in the PMA mouse model of human clubfoot was mapped and a candidate gene, Limk1 , identified that was shown to cause sciatic nerve and limb abnormalities when overexpressed. Limk1 Axon guidance Clubfoot Limb development Chicken Congenital talipes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (2): dev151548.
Published: 17 January 2018
..., but also selectively requires tyrosine phosphorylation of the receptor. Notch Tyrosine phosphorylation Proteolytic cleavage Abl Disabled Trio Axon guidance The receptor Notch and its associated signaling pathway are essential for the development of nearly every cell type...