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Keywords: Axis formation
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Journal Articles
Journal: Development
Development (2022) 149 (7): dev200125.
Published: 30 March 2022
... et al., 2013 ). Together with these observations, the identification of a planarian Src that collaborates with Wnt-dependent processes supports a potentially ancient connection between these factors for axis formation. Fig. 6. src-1 acts with Wnt and FGFRLs to control AP axis identity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (9): dev198101.
Published: 29 April 2021
... dorsal development and anterior neuroectoderm pattern formation in zebrafish embryos. Thus, EIF4A3/Eif4a3 functions not only as a Wnt/β-catenin signaling repressor but also as a regulator of axis formation during zebrafish embryogenesis. Eukaryotic initiation factor 4A3 (EIF4A3; also known as DDX48...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (7): dev192344.
Published: 6 April 2021
... niches of the olfactory/GnRH systems . J. Neurosci. 33 , 19620 - 19634 . 10.1523/JNEUROSCI.3238-13.2013 François , V. and Bier , E. ( 1995 ). Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation . Cell...
Journal Articles
Journal: Development
Development (2016) 143 (10): 1766–1777.
Published: 15 May 2016
... , 707 - 719 . 10.1093/icb/icq076 Holstein , T. W. , Watanabe , H. and Özbek , S. ( 2011 ). Signaling pathways and axis formation in the lower metazoa . Curr. Top. Dev. Biol.   97 , 137 - 177 . 10.1016/B978-0-12-385975-4.00012-7 Kiecker , C. and Niehrs , C...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 2984–2992.
Published: 1 August 2014
.... Consistent with this, overexpression of the aPKC antagonist Lgl strongly rescues the polarity defects of slmb mutant germline clones. The role of Slmb in oocyte polarity raises an intriguing parallel with C. elegans axis formation, in which PAR-2 excludes the anterior PAR complex from the posterior cortex...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 719–729.
Published: 15 February 2013
... no competing financial interests. 30 10 2012 © 2013. Published by The Company of Biologists Ltd 2013 Axis formation Eye Homeodomain pbx Planarians Regeneration Planarians are capable of regenerating any missing body part and are an emerging system for investigation of cellular...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 362–371.
Published: 15 January 2013
...@embl.de ) Competing interests statement The authors declare no competing financial interests. 30 10 2012 © 2013. Published by The Company of Biologists Ltd Cdc42 aPKC Par-6 Bazooka Actin Polarity Oogenesis Axis formation Drosophila Cell...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 2903–2915.
Published: 15 August 2012
...Shimin Lim; Pooja Kumari; Patrick Gilligan; Helen Ngoc Bao Quach; Sinnakaruppan Mathavan; Karuna Sampath Despite extensive study, the earliest steps of vertebrate axis formation are only beginning to be elucidated. We previously showed that asymmetric localization of maternal transcripts...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: Primer Series
Development (2012) 139 (15): 2655–2662.
Published: 1 August 2012
... ), has also been observed in Parasteatoda ( Kanayama et al., 2011 ; Montgomery, 1909 ; Oda et al., 2007 ). In Drosophila , anteroposterior (AP) axis formation and patterning are regulated by maternal gene products that are deposited and localised in the eggs. However, the specific factors...
Journal Articles
Journal: Development
Development (2011) 138 (17): 3759–3767.
Published: 1 September 2011
... Association Established Investigator Award (B.G.B.). Epigenetic regulators other than Ezh2 are likely to influence axis formation. We anticipate that other limb conditional mutants will reveal exciting insights, including further details regarding the mechanisms by which the proximodistal axis...
Journal Articles
Journal: Development
Development (2011) 138 (16): 3497–3507.
Published: 15 August 2011
...Megan J. Wilson; Peter K. Dearden Axis formation is a key step in development, but studies indicate that genes involved in insect axis formation are relatively fast evolving. Orthodenticle genes have conserved roles, often with hunchback , in maternal anterior patterning in several insect species...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (18): 3057–3066.
Published: 15 September 2010
...David J. Duffy; Günter Plickert; Timo Kuenzel; Wido Tilmann; Uri Frank We studied the role of Wnt signaling in axis formation during metamorphosis and regeneration in the cnidarian Hydractinia . Activation of Wnt downstream events during metamorphosis resulted in a complete oralization...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (10): 1765–1773.
Published: 15 May 2010
... determination, demonstrating that Baz is essential for axis formation. The dynamics of Baz, Par-6 and Par-1 localisation in the oocyte indicate that the axis is not polarised by a cortical contraction as in C. elegans , and instead suggest that repolarisation of the oocyte is triggered by posterior inactivation...
Journal Articles
Journal: Development
Development (2010) 137 (8): 1263–1273.
Published: 15 April 2010
... 2010. Axis formation Cell migration Patched Hedgehog Smoothened Dpp RNAi Achaearanea tepidariorum Spider The migration of a signaling source is a common strategy for directing the activation or inhibition of a signaling pathway in the appropriate regions during...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (10): 1675–1685.
Published: 15 May 2009
... Chordin Noggin Follistatin-like Axis formation DV patterning Zebrafish Organizer Formation of the vertebrate body plan depends on the organizer. Originally identified in amphibians ( Spemann and Mangold, 1924 ) and later in fish( Ho, 1992 ; Oppenheimer, 1934 ; Saúde et al...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (3): 501–511.
Published: 1 February 2008
... developmental abnormalities in Eomes/Nodal double heterozygotes, and demonstrate that these phenotypes reflect Eomes and Nodal interactions in different tissue sites. Collectively, our experiments establish that Eomes is a key regulator of anteroposterior axis formation, EMT and definitive endoderm...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1397–1406.
Published: 1 April 2007
... © 2007. 2007 Limb bud Axis formation Cell fate Boundary Chick Pattern formation during development is a complicated process that includes cell proliferation, migration, death and differentiation and is sometimes accompanied by subdivision of an area into domains with different...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (3): 503–513.
Published: 1 February 2007
...-axis formation were consistently recovered by the injection of mouse LRP6 mRNA ( Fig. 1G ), showing the requirement for LRP6 in this process. As further confirmation that LRP6 was required to activate the canonical Wnt signaling pathway, we used the TOPflash reporter to examine the effects...
Journal Articles
Journal: Development
Development (2006) 133 (22): 4517–4526.
Published: 15 November 2006
... ). * Author for correspondence (e-mail: danilchi@ohsu.edu ) 13 9 2006 © 2006. 2006 Axis formation Left-right asymmetry Xenopus laevis Actin Microtubule Egg Cytoskeleton The first steps in embryonic patterning involve the specification of major body axes. In many organisms...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (17): 3379–3387.
Published: 1 September 2006
... are asymmetrically expressed by 4.5 days. † Author for correspondence (e-mail: claire.chazaud@inserm.u-clermont1.fr ) * Present address: Inserm, U384, Clermont-Ferrand, F-63001, France 27 6 2006 © 2006. 2006 Mouse embryogenesis Axis formation Wnt Chimera Asymmetry Mouse...