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Keywords: Axis formation
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Journal Articles
Journal: Development
Development (2021) 148 (9): dev198101.
Published: 29 April 2021
... signaling and regulates zebrafish axis formation by interfering with the formation of the β-catenin/Tcf transcription activation complex. EIF4A3 Wnt/β-catenin signaling β-catenin Lef/Tcf Zebrafish Axis formation Wnt/β-catenin signaling plays pivotal roles in regulating embryogenesis in...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (7): dev192344.
Published: 06 April 2021
... morphogen gradient patterning in diverse developmental contexts including in Tribolium , Drosophila , Xenopus and zebrafish early embryos, as well as the Drosophila wing imaginal disc and germarium. Morphogen gradient BMP patterning Zebrafish Drosophila Axis formation The core bone...
Journal Articles
Journal: Development
Development (2016) 143 (10): 1766–1777.
Published: 15 May 2016
.... ( 2010 ). beta-catenin and early development in the gastropod, Crepidula fornicata . Integr. Comp. Biol.   50 , 707 - 719 . 10.1093/icb/icq076 Holstein , T. W. , Watanabe , H. and Özbek , S. ( 2011 ). Signaling pathways and axis formation in the lower metazoa . Curr. Top. Dev...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 2984–2992.
Published: 01 August 2014
.... Consistent with this, overexpression of the aPKC antagonist Lgl strongly rescues the polarity defects of slmb mutant germline clones. The role of Slmb in oocyte polarity raises an intriguing parallel with C. elegans axis formation, in which PAR-2 excludes the anterior PAR complex from the posterior cortex to...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 719–729.
Published: 15 February 2013
... authors declare no competing financial interests. 30 10 2012 © 2013. Published by The Company of Biologists Ltd 2013 Axis formation Eye Homeodomain pbx Planarians Regeneration Planarians are capable of regenerating any missing body part and are an emerging system for...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 362–371.
Published: 15 January 2013
... . Tomancak P. , Piano F. , Riechmann V. , Gunsalus K. C. , Kemphues K. J. , Ephrussi A. ( 2000 ). A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation . Nat. Cell Biol. 2 , 458 – 460 . Vaccari T...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (16): 2903–2915.
Published: 15 August 2012
...Shimin Lim; Pooja Kumari; Patrick Gilligan; Helen Ngoc Bao Quach; Sinnakaruppan Mathavan; Karuna Sampath Despite extensive study, the earliest steps of vertebrate axis formation are only beginning to be elucidated. We previously showed that asymmetric localization of maternal transcripts of the...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: Primer Series
Development (2012) 139 (15): 2655–2662.
Published: 01 August 2012
... stage 3 ( Akiyama-Oda and Oda, 2010 ). * Author for correspondence ( amcgregor@brookes.ac.uk ) Competing interests statement The authors declare no competing financial interests. © 2012. 2012 Axis formation Evolution Gene regulation Segmentation Spiders The...
Journal Articles
Journal: Development
Development (2011) 138 (17): 3759–3767.
Published: 01 September 2011
... statement The authors declare no competing financial interests. 26 6 2011 © 2011. Ezh2 Hox Polycomb Axis formation Limb bud Plasticity Mouse Pattern formation in many embryonic contexts follows the acquisition of regionally distinct positional identities by...
Journal Articles
Journal: Development
Development (2011) 138 (16): 3497–3507.
Published: 15 August 2011
...Megan J. Wilson; Peter K. Dearden Axis formation is a key step in development, but studies indicate that genes involved in insect axis formation are relatively fast evolving. Orthodenticle genes have conserved roles, often with hunchback , in maternal anterior patterning in several insect species...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (18): 3057–3066.
Published: 15 September 2010
...David J. Duffy; Günter Plickert; Timo Kuenzel; Wido Tilmann; Uri Frank We studied the role of Wnt signaling in axis formation during metamorphosis and regeneration in the cnidarian Hydractinia . Activation of Wnt downstream events during metamorphosis resulted in a complete oralization of the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (10): 1765–1773.
Published: 15 May 2010
... determination, demonstrating that Baz is essential for axis formation. The dynamics of Baz, Par-6 and Par-1 localisation in the oocyte indicate that the axis is not polarised by a cortical contraction as in C. elegans , and instead suggest that repolarisation of the oocyte is triggered by posterior inactivation...
Journal Articles
Journal: Development
Development (2010) 137 (8): 1263–1273.
Published: 15 April 2010
... ) Competing interests statement 3 2 2010 © 2010. Axis formation Cell migration Patched Hedgehog Smoothened Dpp RNAi Achaearanea tepidariorum Spider For information about the cDNAs used in this study, see Table S1 in the supplementary material . cDNA...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (10): 1675–1685.
Published: 15 May 2009
.... Thus, gsc -overexpressing cells populated tissues normally derived from the shield. * Author for correspondence (e-mail: ashley.bruce@utoronto.ca ) 10 3 2009 © 2009. 2009 Goosecoid Chordin Noggin Follistatin-like Axis formation DV patterning Zebrafish...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (3): 501–511.
Published: 01 February 2008
... developmental abnormalities in Eomes/Nodal double heterozygotes, and demonstrate that these phenotypes reflect Eomes and Nodal interactions in different tissue sites. Collectively, our experiments establish that Eomes is a key regulator of anteroposterior axis formation, EMT and definitive endoderm...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1397–1406.
Published: 01 April 2007
... © 2007. 2007 Limb bud Axis formation Cell fate Boundary Chick Pattern formation during development is a complicated process that includes cell proliferation, migration, death and differentiation and is sometimes accompanied by subdivision of an area into domains with different and...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (3): 503–513.
Published: 01 February 2007
... exist in simple off or on states, but may also include a third, steady-state, modality. * Author for correspondence (e-mail: heabq9@chmcc.org ) 14 11 2006 © 2007. 2007 Xenopus β-catenin Wnt11 LRP6 Axis formation The single-pass transmembrane protein, LDL receptor...
Journal Articles
Journal: Development
Development (2006) 133 (22): 4517–4526.
Published: 15 November 2006
.... * Author for correspondence (e-mail: danilchi@ohsu.edu ) 13 9 2006 © 2006. 2006 Axis formation Left-right asymmetry Xenopus laevis Actin Microtubule Egg Cytoskeleton The first steps in embryonic patterning involve the specification of major body axes. In many organisms...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (17): 3379–3387.
Published: 01 September 2006
... markers are asymmetrically expressed by 4.5 days. Activation of Wnt signaling in the embryo also implicates Wnt pathways in axis formation in mice. Misexpression of chick Wwnt8c in transgenic lines produces a range of defects including ectopic embryonic axes( Popperl et al., 1997 ). Axin1 mutations...
Journal Articles
Journal: Development
Development (2006) 133 (14): 2757–2770.
Published: 15 July 2006
...Gerlinde Reim; Michael Brand Dorsoventral (DV) axis formation of the vertebrate embryo is controlled by the maternal genome and is subsequently refined zygotically. In the zygote,repression of ventralizing Bmp activity on the dorsal side through chordin and noggin is crucial for establishment of a...
Includes: Supplementary data