... and regenerative medicine. Axis elongation Gastrulation Neuromesodermal progenitors Primitive streak Tail bud Pluripotent stem cells Lineage specification in the early vertebrate embryo is initiated during gastrulation (see Glossary, Box 1 ), which involves the formation of the three germ...

...Bertrand Bénazéraf; Mathias Beaupeux; Martin Tchernookov; Allison Wallingford; Tasha Salisbury; Amelia Shirtz; Andrew Shirtz; David Huss; Olivier Pourquié; Paul François; Rusty Lansford Embryonic axis elongation is a complex multi-tissue morphogenetic process responsible for the formation...

...Bambang Retnoaji; Ryutaro Akiyama; Tatsuro Matta; Yasumasa Bessho; Takaaki Matsui During vertebrate development, the primary body axis elongates towards the posterior and is periodically divided into somites, which give rise to the vertebrae, skeletal muscles and dermis. Somites form periodically...

...Anke Beermann; Romy Prühs; Rebekka Lutz; Reinhard Schröder Short germ embryos elongate their primary body axis by consecutively adding segments from a posteriorly located growth zone. Wnt signalling is required for axis elongation in short germ arthropods, including Tribolium castaneum...

... Cdx Vertebral patterning Axis elongation Brachyury Wnt3a Retinoic acid CYP26a1 Mouse Cdx2 -null mutants exhibited reduced expression of Cdx4. As Cdx members exhibit extensive functional overlap, at least as regards vertebral patterning ( van den Akker et al., 2002 ; Savory et al...

... that control axis elongation of the mouse embryo are much less well understood. Here, we characterize the ENU-induced mouse mutation chato , which causes arrest at midgestation and defects characteristic of convergent extension mutants, including a shortened body axis, mediolaterally extended somites...