... an embryonic process that played a fundamental step in the evolution of avian flight. To determine whether Shh signalling specifies feather identity in the chick wing, we transiently inhibited it using cyclopamine at day 3 of incubation (HH19) for ∼72 h ( Pickering and Towers, 2016 ). Cyclopamine is a potent...

... species and is posited to control avian germ cell formation. We show that TALENs mediate homology-directed repair of the DDX4 locus on the Z sex chromosome at high (8.1%) efficiencies. Large genetic deletions of 30 kb encompassing the entire DDX4 locus were also created using a single TALEN pair...

... Avian Quail The first hematopoietic stem/progenitor cells (HSPCs) emerge during the initial phase of embryonic development in the form of cell aggregates, designated hematopoietic clusters, that are intimately associated with endothelial cells (ECs) in the floor of the dorsal aorta...

... The authors declare no competing financial interests. 10 4 2013 © 2013. Published by The Company of Biologists Ltd 2013 Amniotes Avian Blastopore Gastrulation Mesoderm Primitive streak The mesoderm is one of the three principle germ layers and is formed during...

... for correspondence ( dalit.seladon@mail.huji.ac.il ) Competing interests statement The authors declare no competing financial interests. 20 3 2013 © 2013. Published by The Company of Biologists Ltd 2013 Pax6 Boundaries Hindbrain Rhombomere Segmentation Avian Mouse...

...Petr Valasek; Raymond Macharia; Winfried L. Neuhuber; Joerg Wilting; David L. Becker; Ketan Patel The lymph heart is a sac-like structure on either side of avian tail. In some adult birds, it empties the lymph from the copulatory organ; however,during embryonic development, it is thought...

... in patterning craniofacial and forebrain structures,but an earlier role in anterior patterning is not well understood. We show that enzymes involved in synthesizing retinoids are expressed in the avian hypoblast and in tissues directly involved in head patterning, such as anterior definitive endoderm...

... of migrating sacral NCC were not resolved. Furthermore, these studies were unable to ascertain the cellular derivatives of sacral NCC within the gut, an important issue that has remained unresolved prior to this current study. Enteric Neuron Glia Neural crest Avian Gut REFERENCES Allan...

... protein product is secreted from transfected cells and interacts with the avian VEGFR3 and VEGFR2. In situ hybridization shows that quail VEGF-C mRNA is strongly expressed in regions destined to be rich in lymphatic vessels, particularly the mesenteries, mesocardium and myotome, in the region surrounding...

...-mail: parker@ns.arizona.edu ) 17 04 1997 © 1997 by Company of Biologists 1997 avian heart hypoblast mesoderm induction myocardium specification epiblast The first mesodermally derived organ to form in many vertebrates is the heart, which initially arises as a simple tube...

... somite explant culture videomicroscopy avian neural crest PNA Neural development involves the orchestration of various processes to generate patterns of cellular architecture and synaptic connectivity that are required for mature function. Precursor cells must migrate to their target regions...

... © 1990 by Company of Biologists 1990 ontogeny immunocytochemistry process outgrowth pathway formation axonal growth pattern propriospinal spinal cord avian Previous studies, including two reports from our labora-tory, have shown that intersegmental projection neur-ons...