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Keywords: Auto-regulation
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Journal Articles

Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch

Dimitrios K. Papadopoulos, Kassiani Skouloudaki, Ylva Engström, Lars Terenius, Rudolf Rigler, Christoph Zechner, Vladana Vukojević, Pavel Tomancak
Journal: Development
Development (2019) 146 (12): dev168179.
https://doi.org/10.1242/dev.168179
Published: 25 January 2019
... of the Hox transcription factor Antennapedia elicit a developmental regulatory switch from auto-activation to auto-repression that increases concentration and suppresses cell-to-cell variability over time. Auto-regulation Fluorescence correlation spectroscopy Hox genes Protein noise Transcription...
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Includes: Supplementary data