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Keywords: Aurora
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Journal Articles
Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis
Nathalie Colombié, C. Fiona Cullen, Amy L. Brittle, Janet K. Jang, William C. Earnshaw, Mar Carmena, Kim McKim, Hiroyuki Ohkura
Journal:
Development
Development (2008) 135 (19): 3239–3246.
Published: 1 October 2008
... remain to be understood. Here, we report two crucial roles of Incenp, an essential subunit of the chromosomal passenger complex (the Aurora B complex), in centrosome-independent spindle formation in Drosophila female meiosis. First, the initial assembly of spindle microtubules is drastically delayed...
Includes: Multimedia, Supplementary data
Journal Articles
Journal:
Development
Development (1998) 125 (22): 4391–4402.
Published: 15 November 1998
...Jill M. Schumacher; Neville Ashcroft; Peter J. Donovan; Andy Golden ABSTRACT S. cerevisiae Ipl1, Drosophila Aurora, and the mammalian centrosomal protein IAK-1 define a new subfamily of serine/threonine kinases that regulate chromosome segregation and mitotic spindle dynamics. Mutations in ipl1...