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Keywords: Asymmetric division
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Journal Articles
Journal: Development
Development (2024) 151 (3): dev200981.
Published: 5 February 2024
... cleavages that are regulated by key proneural transcription factors. Asymmetric division Neuronal specification Proneural C . elegans Wellcome Trust http://dx.doi.org/10.13039/100010269 207483/Z/17/Z 105380/Z/14/Z Biotechnology and Biological Sciences Research Council...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (10): dev201409.
Published: 25 May 2023
... © 2023. Published by The Company of Biologists Ltd 2023 Highlighted Article: ESCRT-III Shrub/CHMP4 exerts two complementary functions during asymmetric division of sensory organ precursors, to coordinate the maintenance of junctional integrity with abscission. ESCRT-III Asymmetric...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev191411.
Published: 28 September 2020
.... Ankle2 Drosophila Asymmetric division Microcephaly Model of human disease Every in vivo approach used to study genetic variants associated with human disease has benefits and caveats. Whether the system is based on human cells in culture, primates, rodents, fish, flies, worms or yeast...
Journal Articles
Journal Articles
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Neural development
Journal: Development
Development (2018) 145 (7): dev160747.
Published: 5 April 2018
... regulatory program. Lineage size Cell cycle Asymmetric division Combinatorial control Nervous system development Evolution of the CNS The central nervous system (CNS) is a defining feature of bilaterally symmetric animals (bilateria), and can be generally subdivided into the brain...
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Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (20): 3774–3784.
Published: 15 October 2016
... © 2016. Published by The Company of Biologists Ltd 2016 Summary: During Drosophila embryonic CNS development, the zinc-finger protein Sequoia interacts with the Notch pathway to control lineage progression. Lineage tree Cell cycle Asymmetric division Combinatorial control Notch...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (8): 1259–1270.
Published: 15 April 2016
...: This Review summarises the transcription factor and epigenetic control of stomatal development and patterning, highlighting similarities between plant and animal developmental mechanisms. Asymmetric division bHLH proteins Epigenetic regulation of differentiation Lineage-specific stem cells Peptide...
Journal Articles
Journal: Development
Development (2015) 142 (9): 1572–1581.
Published: 1 May 2015
... re-enter the cell cycle to proliferate and subsequently exit the cell cycle to differentiate or self-renew. Recent studies have demonstrated that satellite cells are heterogeneous and that subpopulations of satellite stem cells are able to perform asymmetric divisions to generate myogenic progenitors...
Journal Articles
Journal Articles
Journal: Development
Development (2014) 141 (14): 2813–2824.
Published: 15 July 2014
...Shihadeh Anani; Shivani Bhat; Nobuko Honma-Yamanaka; Dayana Krawchuk; Yojiro Yamanaka In the mouse embryo, asymmetric divisions during the 8-16 cell division generate two cell types, polar and apolar cells, that are allocated to outer and inner positions, respectively. This outer/inner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1842–1850.
Published: 15 May 2012
... the asymmetric division, showing the commitment of the future daughter cell to differentiation. The coordination of these two alternative cell cycles contributes to the continuous production of infective parasites, turning the tsetse fly into an efficient and long-lasting vector for African trypanosomes. We...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (20): 4375–4385.
Published: 15 October 2011
...Marjolein Wildwater; Nicholas Sander; Geert de Vreede; Sander van den Heuvel Tissue-specific stem cells combine proliferative and asymmetric divisions to balance self-renewal with differentiation. Tight regulation of the orientation and plane of cell division is crucial in this process. Here, we...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (14): 2903–2908.
Published: 15 July 2011
... 2011. 2011 F-actin Asymmetric division Meiosis Mouse Oocyte Asymmetric cell division requires correct spindle positioning with regards to the polarity axis of the mother cell ( Gonczy, 2008 ). In most models, mitotic spindle positioning depends on pulling forces produced by astral...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (5): 831–837.
Published: 1 March 2011
..., we report that CySCs divide asymmetrically through repositioning the mitotic spindle around anaphase. CySC spindle repositioning requires functional centrosomes, Dynein and the actin-membrane linker Moesin. Anaphase spindle repositioning is required to achieve high-fidelity asymmetric divisions...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (5): 715–724.
Published: 1 March 2010
... to this work † Present address: Rosalind and Morris Goodman Cancer Center, Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, Quebec H3A 1A3, Canada Competing interests statement 30 12 2009 © 2010. ICM Asymmetric division Primitive endoderm...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (20): 3393–3397.
Published: 15 October 2009
...Elena Rebollo; Mónica Roldán; Cayetano Gonzalez Spindle alignment along the apicobasal polarity axis is mandatory for proper self-renewing asymmetric division in Drosophila neuroblasts(NBs). In embryonic NBs, spindles have been reported to assemble orthogonally to the polarity axis and later...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (13): 2287–2296.
Published: 1 July 2009
...-renewal and differentiation Drosophila Neural stem cell Neuroblast Asymmetric division Drosophila larval brain neuroblasts, also known as neural stem cells (NSCs), divide asymmetrically to give rise to a self-renewing daughter,that continues to divide asymmetrically, and a ganglion mother...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (11): 1801–1812.
Published: 1 June 2009
...-linear mechanisms that can occur in multiple orders and combinations to allow neural crest cells to escape from the neuroepithelium. e-mails: jdahlstrom@ucdavis.edu ; caerickson@ucdavis.edu 23 3 2009 © 2009. 2009 EMT Asymmetric division Chicken Live cell imaging Neural crest...
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Journal Articles
Journal: Development
Development (2008) 135 (18): 3001–3005.
Published: 15 September 2008
... indicate that the vast majority, if not all, of GFP-labeled p2 progenitors divide once to produce V2a/V2b neuron pairs,indicating that V2a and V2b neurons are generated by the asymmetric division of pair-producing progenitor cells. Together with evidence that Notch signaling is involved in the cell fate...
Includes: Multimedia, Supplementary data