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Keywords: Astrocytes
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (5): dev201047.
Published: 1 March 2023
... understood. Previous reports indicate a role for microglia in regulating astrocyte density. This current work resolves the mechanism through which microglia facilitate astrocyte spatial patterning and superficial vascular bed formation in the neuroretina during development. Ablation of microglia increased...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (15): dev200750.
Published: 2 August 2022
...Maria Micaela Sartoretti; Carla A. Campetella; Guillermo M. Lanuza ABSTRACT Significant progress has been made in elucidating the basic principles that govern neuronal specification in the developing central nervous system. In contrast, much less is known about the origin of astrocytic diversity...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (9): dev182279.
Published: 1 May 2020
... fail to regress in RGC-deficient retinas ( Edwards et al., 2012 ; Rao et al., 2013 ; Sapieha et al., 2008 ). As VEGFA is secreted by multiple cell types in the retina ( Fig. 4 B), a recent study sought to resolve the roles of astrocyte-derived versus neuronal/Müller glia-derived VEGFA in retinal...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (4): dev155275.
Published: 23 February 2018
...Grégory Ghézali; Charles-Félix Calvo; Laure-Elise Pillet; Flora Llense; Pascal Ezan; Ulrike Pannasch; Alexis-Pierre Bemelmans; Sandrine Etienne Manneville; Nathalie Rouach ABSTRACT Astrocytes undergo intense morphological maturation during development, changing from individual sparsely branched...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (13): 2398–2409.
Published: 1 July 2016
... the liver. However, its role in the brain remains unclear. Here, we provide evidence for YAP regulation of mouse neocortical astrocytic differentiation and proliferation. YAP was undetectable in neurons, but selectively expressed in neural stem cells (NSCs) and astrocytes. YAP in NSCs was required...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (7): 1594–1604.
Published: 1 April 2013
... studies suggesting an important requirement for Shh FP in specifying oligodendrocyte cell fates via repression of Gli3 in progenitors. Our studies also uncover a connection between embryonic Shh signaling and astrocyte-mediated reactive gliosis in adults, raising the possibility that this pathway...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (8): 1855–1862.
Published: 15 April 2005
...Heloise West; William D. Richardson; Marcus Fruttiger Development of the retinal vasculature is controlled by a hierarchy of interactions among retinal neurons, astrocytes and blood vessels. Retinal neurons release platelet-derived growth factor (PDGFA) to stimulate proliferation of astrocytes...
Journal Articles
Journal: Development
Development (2005) 132 (8): 1951–1959.
Published: 15 April 2005
... signalling. Dbx-expressing precursors also generate astrocytes and interneurons, but do not contribute to the ependymal layer of the postnatal spinal cord. * Author for correspondence (e-mail: w.richardson@ucl.ac.uk ) To generate mice expressing Cre recombinase under Dbx1 transcriptional control...
Journal Articles
Journal Articles
Journal: Development
Development (1991) 113 (1): 129–140.
Published: 1 September 1991
... vessels and accessory astrocytes, express neurothelin. Here we demonstrate that during chick brain development initially neurothelin is expressed probably in all neuroblasts. With proceeding cytodifferentiation, such as vascularization and gliogenesis, brain neurons become neurothelin negative...
Journal Articles
Journal: Development
Development (1991) 113 (1): 353–362.
Published: 1 September 1991
...Robert H. Miller; Vilma Szigeti Summary Within the mammalian CNS, astrocytes appear to be a heterogeneous class of cells. To assay the number of distinct types of astrocytes in the rat spinal cord, cell lineage and phenotypic analyses were carried out on cultures from newborn rat spinal cord...