...Eleanor Gilbert; Callum Teeling; Tatiana Lebedeva; Siffreya Pedersen; Nathan Chrismas; Grigory Genikhovich; Vengamanaidu Modepalli ABSTRACT Cnidarians are the only non-bilaterian group to evolve ciliated larvae with an apical sensory organ, which is possibly homologous to the apical organs...

... and NvFrizzled5/8 are both expressed in the aboral domain, but they have opposing activities, with NvSix3/6 maintaining and NvFrizzled5/8 restricting the size of the aboral domain. At planula stage, NvFrizzled5/8 is required for patterning within the aboral domain and for regulating the size of the apical organ...

... us with insights into the evolution of deuterostome (see Glossary, Box 1 ) nervous systems. Wnt TGFβ Nodal BMP Dorsal-ventral axis Anterior-posterior axis Lefty Chordin Six3 FoxQ2 Ciliary band Apical organ Ectoderm patterning Neural development...

... signalling in a non-bilaterian animal, the sea anemone Nematostella vectensis . We identified the complete set of FGF ligands and FGF receptors, of which two paralogous FGFs ( NvFGFa1 and NvFGFa2 ) and one FGF receptor( NvFGFRa ) are specifically coexpressed in the developing apical organ, a sensory...