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Keywords: Anterior primitive streak
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Journal Articles
Journal:
Development
Development (2004) 131 (15): 3501–3512.
Published: 1 August 2004
... limited. We have employed a Smad4 conditional allele to specifically inactivate the Smad4 gene in the early mouse epiblast. Loss of Smad4 in this tissue results in a profound failure to pattern derivatives of the anterior primitive streak, such as prechordal plate, node, notochord and definitive endoderm...
Includes: Supplementary data