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Keywords: Angiopoietin
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Journal Articles
Sujata Rao, Ivan B. Lobov, Jefferson E. Vallance, Kaoru Tsujikawa, Ichiro Shiojima, Shailaja Akunuru, Kenneth Walsh, Laura E. Benjamin, Richard A. Lang
Journal:
Development
Development (2007) 134 (24): 4449–4458.
Published: 15 December 2007
... cell death. Here we show that during developmentally scheduled vascular regression,resident macrophages are an obligatory participant in a signaling switch that favors death over survival. This switch occurs when the signaling ligand angiopoietin 2 has the dual effect of suppressing survival signaling...