...Adam W. Olson; Vien Le; Jinhui Wang; Alex Hiroto; Won Kyung Kim; Dong-Hoon Lee; Joseph Aldahl; Xiwei Wu; Minhyung Kim; Gerald R. Cunha; Sungyong You; Zijie Sun ABSTRACT Stromal androgen-receptor (AR) action is essential for prostate development, morphogenesis and regeneration. However, mechanisms...

... position relative to the smooth muscle layer. In vitro recombination experiments demonstrated that direct contact with the VMP led to the induction of very few epithelial buds, and that androgens dramatically increased bud development. Taken together, our data suggest that differentiation of a smooth...

...Ryutaro Murakami; Takeo Mizuno The penis of adult rats comprises the corpus cavernosum penis and the proximal and distal segments of os penis which are situated proximal-distally in this order. Androgens are necessary for the phenotypic differentiation of these tissues. In the present study...