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Keywords: Anaphase promoting complex
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Journal Articles

HECT-E3 ligase ETC-1 regulates securin and cyclin B1 cytoplasmic abundance to promote timely anaphase during meiosis in C. elegans

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Ruishan Wang, Zeenia Kaul, Charuta Ambardekar, Takaharu G. Yamamoto, Kanisha Kavdia, Kiran Kodali, Anthony A. High, Risa Kitagawa
Journal: Development
Development (2013) 140 (10): 2149–2159.
https://doi.org/10.1242/dev.090688
Published: 15 May 2013
..., the E3 ligase anaphase promoting complex/cyclosome (APC/C) ubiquitylates securin for proteolysis, triggering sister chromatid separation. Securin is also implicated in regulating meiotic progression. Securin protein levels change sharply during cell cycle progression, enabling its timely action...
View articletitled, HECT-E3 ligase ETC-1 regulates securin and cyclin B1 cytoplasmic abundance to promote timely anaphase during meiosis in C. elegans
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Includes: Supplementary data
Journal Articles

Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome

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Cathy Slack, Paul M. Overton, Richard I. Tuxworth, William Chia
Journal: Development
Development (2007) 134 (21): 3781–3787.
https://doi.org/10.1242/dev.010900
Published: 1 November 2007
... ganglion mother cell (GMC). The asymmetric localisation of neural cell fate determinants and their adapter proteins to the neuroblast cortex during mitosis facilitates their preferential segregation to the GMC upon cytokinesis. In this study we report a novel role for the anaphase-promoting complex...
View articletitled, Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome
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Includes: Supplementary data
Journal Articles

Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase

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Joshua N. Bembenek, Christopher T. Richie, Jayne M. Squirrell, Jay M. Campbell, Kevin W. Eliceiri, Dmitry Poteryaev, Anne Spang, Andy Golden, John G. White
Journal: Development
Development (2007) 134 (21): 3837–3848.
https://doi.org/10.1242/dev.011361
Published: 1 November 2007
... material). These results demonstrate that cortical granule exocytosis occurs during anaphase I. * Author for correspondence (e-mail: [email protected]) 13 8 2007 © 2007. 2007 Anaphase promoting complex Cortical granule exocytosis Egg activation Separase Spindle assembly...
View articletitled, Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase
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Includes: Multimedia, Supplementary data