...Leah B. Nantie; Randee E. Young; Wyatt G. Paltzer; Yan Zhang; Randy L. Johnson; Jamie M. Verheyden; Xin Sun ABSTRACT Lung growth to its optimal size at birth is driven by reiterative airway branching followed by differentiation and expansion of alveolar cell types. How this elaborate growth...

... that the original work is properly attributed. Summary: This Review describes how recent technological advances have shed light on the mechanisms underlying human lung development and disease, and outlines the future challenges in this field. Bronchi Alveolar ESC iPSC Progenitor Stem cell Lung...

... littermates. In the absence of CARM1, alveolar type II cells show increased proliferation. Electron microscopic analyses demonstrate that lungs from mice lacking CARM1 have immature alveolar type II cells and an absence of alveolar type I cells. Gene expression analysis reveals a dysregulation of cell cycle...