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Keywords: Allele-specific expression
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Journal Articles
Journal: Development
Development (2018) 145 (7): dev160622.
Published: 29 March 2018
... methylation. Nevertheless, the role of TET1 in demethylating ICRs in the female germline and in controlling allele-specific expression remains unknown. Here, we examined ICR-specific DNA methylation in Tet1 −/− germ cells and ascertained whether abnormal ICR methylation impacted imprinted gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (22): 4161–4166.
Published: 15 November 2016
... diseases. Our ability to interrogate causes of imprinting instability has been hindered by the absence of suitable model systems. Here, we describe a Dlk1 knock-in reporter mouse that enables single-cell visualization of allele-specific expression and prospective isolation of cells, simultaneously. We show...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (3): 437–448.
Published: 1 February 2009
... 1 12 2008 © 2009. 2009 Embryonic stem (ES) cells Epigenetics Genomic imprinting ES in vitro imprinting model ncRNA Histone modifications DNA methylation Allele-specific expression Airn ( Air ) To study imprinted expression at the Igf2r cluster we used two inbred 129...
Includes: Supplementary data