.... Summary: The muscarinic acetylcholine receptor subtype M4 (M4 mAChR) is expressed in a subpopulation of neural precursor cells in the adult mouse hippocampus, where is plays a stage-specific role in neurogenesis. Adult neurogenesis Neural precursor cells Hippocampus Acetylcholine Cholinergic...

.... , Rodriguez , R. R. , Gonzalez-Granero , S. , García-Verdugo , J. M. , Lim , D. A. et al. ( 2021 ). Single-cell analysis of the ventricular-subventricular zone reveals signatures of dorsal and ventral adult neurogenesis . eLife 10 , e67436 . 10.7554/eLife.67436.sa2 Chapman...

..., the olfactory system continues to mature and change throughout life as a target of constitutive adult neurogenesis. Our Review synthesises current knowledge of prenatal, postnatal and adult olfactory bulb development, focusing on the maturation, morphology, functions and interactions of its diverse constituent...

... of young mice. Adult neurogenesis Adult stem cells Quiescence Wnt Francis Crick Institute http://dx.doi.org/10.13039/100010438 Cancer Research UK http://dx.doi.org/10.13039/501100000289 FC0010089 Medical Research Council FC0010089 Wellcome Trust...

... of mature neurons. Many transcription factors are continuously expressed during this process but it is presently unclear how these factors modify their targets as cells transition through different stages of specification. In olfactory bulb adult neurogenesis, the transcription factor PBX1 controls...

...Christian Lange; Fabian Rost; Anja Machate; Susanne Reinhardt; Matthias Lesche; Anke Weber; Veronika Kuscha; Andreas Dahl; Steffen Rulands; Michael Brand ABSTRACT Zebrafish display widespread and pronounced adult neurogenesis, which is fundamental for their regeneration capability after central...

.... ( 2010 ). Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences . Genome Biol.   11 , R86 . 10.1186/gb-2010-11-8-r86 Gonçalves , J. T. , Schafer , S. T. and Gage , F. H. ( 2016 ). Adult neurogenesis...

.../ Summary: mRNA electroporation is a powerful new method for functional studies in neonatal and adult neural stem cells as well as postmitotic neurons. Adult neurogenesis Subventricular zone Olfactory bulb Cortex Dicer microRNA pathway Manipulation of gene expression in the brain...

... bulb neurons within the SVZ is required for novel odor discrimination ( Livneh et al., 2014 ). Given the important functions of the hypothalamus in physiological homeostasis, it is reasonable to assume that adult neurogenesis there may regulate responses to environmental stimuli. The phenotype...

... to maintain a proper balance between self-renewal and differentiation towards neuronal or glial lineages. TALE-homeodomain protein Adult neurogenesis Subventricular zone Cell fate specification Doublecortin Pioneer factor Highlighted article: The TALE-homeodomain protein PBX1 promotes...

... that was presented at the Fusion meeting on Adult Neurogenesis, which was held in March 2016 in Cancun, Mexico. Adult neurogenesis Hippocampus Human pluripotent stem cell Neural stem cell Neurological disease Subventricular zone The human brain is complex, with millions of neuronal subtypes...

... discusses the extent to which astrocytes in different brain regions can behave as neural stem cells, and the molecular and environmental factors that either promote or repress such activity. Adult neurogenesis Neurogenic regions Parenchymal astrocytes Quiescent stem cells Reprogramming...

... experiments using postnatal or adult SVZ progenitors reveal key differences in the connective properties of the neurons generated. Adult neurogenesis Synaptic development Fate determination Subventricular zone Rat New neurons are continuously added to the adult mammalian brain. The most...

... ). p53 suppresses the self-renewal of adult neural stem cells . Development 133 , 363 - 369 . 10.1242/dev.02208 Ming , G.-l. and Song , H. ( 2005 ). Adult neurogenesis in the mammalian central nervous system . Annu. Rev. Neurosci. 28 , 223 - 250 . 10.1146/annurev.neuro...

..., we know little about the genetic and molecular control of postembryonic neurogenesis. Drosophila Adult neurogenesis Hb9 Gene expression map © 2014. Published by The Company of Biologists Ltd 2014 14 8 2013 16 12 2013 Competing interests The authors...

... Competing interests The authors declare no competing financial interests. 8 4 2013 3 10 2013 © 2014. Published by The Company of Biologists Ltd 2014 Pax6 TALE-homeodomain proteins Adult neurogenesis Subventricular zone Mouse The subventricular zone (SVZ...

..., the fate of neuronal progenitors becomes more restricted, and they generate only a subset of neurons. Here, we review studies of postnatal and adult neurogenesis, challenging the notion that fixed genetic programs restrict neuronal fate. We hypothesize that the adult brain maintains plastic neural stem...

... B. , Chapouton P. , Lam C. S. , Topp S. , Tannhäuser B. , Strähle U. , Götz M. , Bally-Cuif L. ( 2006 ). Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon . Dev. Biol. 295 , 278 - 293 . Agasse F. , Bernardino...

... in the neocortex and may act as progenitors for adult neurogenesis. References Adachi K. , Mirzadeh Z. , Sakaguchi M. , Yamashita T. , Nikolcheva T. , Gotoh Y. , Peltz G. , Gong L. , Kawase T. , Alvarez-Buylla A. , et al . ( 2007 ). Beta-catenin signaling...

.... Neurosci. 30 , 10484 - 10492 . Adolf B. , Chapouton P. , Lam C. S. , Topp S. , Tannhauser B. , Strahle U. , Gotz M. , Bally-Cuif L. ( 2006 ). Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon . Dev. Biol. 295 , 278...