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Keywords: Adult neurogenesis
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Journal Articles
Journal: Development
Development (2020) 147 (8): dev186841.
Published: 13 April 2020
... of mature neurons. Many transcription factors are continuously expressed during this process but it is presently unclear how these factors modify their targets as cells transition through different stages of specification. In olfactory bulb adult neurogenesis, the transcription factor PBX1 controls...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (1): dev185595.
Published: 09 January 2020
...Christian Lange; Fabian Rost; Anja Machate; Susanne Reinhardt; Matthias Lesche; Anke Weber; Veronika Kuscha; Andreas Dahl; Steffen Rulands; Michael Brand ABSTRACT Zebrafish display widespread and pronounced adult neurogenesis, which is fundamental for their regeneration capability after central...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (3): dev155689.
Published: 07 February 2018
.... ( 2010 ). Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences . Genome Biol.   11 , R86 . 10.1186/gb-2010-11-8-r86 Gonçalves , J. T. , Schafer , S. T. and Gage , F. H. ( 2016 ). Adult neurogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (21): 3968–3977.
Published: 01 November 2017
.../ Summary: mRNA electroporation is a powerful new method for functional studies in neonatal and adult neural stem cells as well as postmitotic neurons. Adult neurogenesis Subventricular zone Olfactory bulb Cortex Dicer microRNA pathway Manipulation of gene expression in the brain...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (9): 1588–1599.
Published: 01 May 2017
... their differentiation. Third, genetic targeting of adult-born neurons can be used to determine their contribution to behavioral plasticity. It is possible that multiple behaviors could be identified that are regulated by adult neurogenesis, with important implications for human health. Furthermore, uncovering...
Journal Articles
Journal: Development
Development (2016) 143 (13): 2281–2291.
Published: 01 July 2016
... ). In vivo analysis of Ascl1 defined progenitors reveals distinct developmental dynamics during adult neurogenesis and gliogenesis . J. Neurosci.   27 , 12764 - 12774 . 10.1523/JNEUROSCI.3178-07.2007 Kohwi , M. , Osumi , N. , Rubenstein , J. L. R. and Alvarez-Buylla , A. ( 2005...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (10): 1649–1654.
Published: 15 May 2016
... for the integration of adult-born granule cells . Neuron   85 , 116 - 130 . 10.1016/j.neuron.2014.11.023 Unlocking the fundamental mechanisms and therapeutic potential of adult neurogenesis remains an important goal. It is clear from this meeting that various aspects – from basic principles...
Journal Articles
Journal: Development
Development (2016) 143 (7): 1075–1086.
Published: 01 April 2016
... neurogenic transcriptional program. References Aimone , J. B. , Li , Y. , Lee , S. W. , Clemenson , G. D. , Deng , W. and Gage , F. H. ( 2014 ). Regulation and function of adult neurogenesis: from genes to cognition . Physiol. Rev.   94 , 991 - 1026 . 10.1152/physrev...
Journal Articles
Journal: Development
Development (2015) 142 (2): 303–313.
Published: 15 January 2015
... experiments using postnatal or adult SVZ progenitors reveal key differences in the connective properties of the neurons generated. Adult neurogenesis Synaptic development Fate determination Subventricular zone Rat New neurons are continuously added to the adult mammalian brain. The most...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (24): 4697–4709.
Published: 15 December 2014
... interests The authors declare no competing financial interests. 17 9 2014 23 10 2014 © 2014. Published by The Company of Biologists Ltd 2014 Adult neurogenesis SIRT1 Self-renewal In the dentate gyrus (DG) of the hippocampus, adult neural stem cells (aNSCs) can undergo...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1011–1021.
Published: 01 March 2014
... Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA. Competing interests The authors declare no competing financial interests. 14 8 2013 16 12 2013 © 2014. Published by The Company of Biologists Ltd 2014 Drosophila Adult neurogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (1): 28–38.
Published: 01 January 2014
... of adult neurogenesis . Genes Dev. 26 , 1010 – 1021 . Hyman-Walsh C. , Bjerke G. A. , Wotton D. ( 2010 ). An autoinhibitory effect of the homothorax domain of Meis2 . FEBS J. 277 , 2584 – 2597 . Karl C. , Couillard-Despres S. , Prang P. , Munding M...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (16): 3303–3309.
Published: 15 August 2013
..., the fate of neuronal progenitors becomes more restricted, and they generate only a subset of neurons. Here, we review studies of postnatal and adult neurogenesis, challenging the notion that fixed genetic programs restrict neuronal fate. We hypothesize that the adult brain maintains plastic neural stem...
Journal Articles
Journal: Development
Development (2013) 140 (12): 2548–2561.
Published: 15 June 2013
... pathways that regulate adult neurogenesis and to define lineage relationships between precursor cells, and should also give insights into the roles of neurotransmitter signaling in brain disorders. Moreover, neurotransmitter-responsive cells are not confined to neurons. Neurotransmitter receptors...
Journal Articles
Journal: Development
Development (2011) 138 (12): 2499–2509.
Published: 15 June 2011
... in the neocortex and may act as progenitors for adult neurogenesis. * Author for correspondence ( tamamaki@kumamoto-u.ac.jp ) Competing interests statement The authors declare no competing financial interests. 22 3 2011 © 2011. 2011 GABA Adult neurogenesis Intermediate progenitor...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (8): 1459–1469.
Published: 15 April 2011
.... Neurosci. 30 , 10484 - 10492 . Adolf B. , Chapouton P. , Lam C. S. , Topp S. , Tannhauser B. , Strahle U. , Gotz M. , Bally-Cuif L. ( 2006 ). Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon . Dev. Biol. 295 , 278...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (24): 4127–4134.
Published: 15 December 2010
.... † Author for correspondence ( andras.simon@ki.se ) * These authors contributed equally to this work Competing interests statement 7 10 2010 © 2010. 6-OHDA Adult neurogenesis Dopamine Midbrain Neuronal stem cell Salamander Abundant production of new...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (2): 261–271.
Published: 15 January 2010
...Tamar Licht; Ronen Eavri; Inbal Goshen; Yael Shlomai; Adi Mizrahi; Eli Keshet The angiogenic factor vascular endothelial growth factor A (VEGF) has been shown to have a role in neurogenesis, but how it affects adult neurogenesis is not fully understood. To delineate a role for VEGF in successive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (4): 675–684.
Published: 15 February 2006
... synergism that augments growth factor-mediated cell proliferation. Together with the in situ data, this supports the notion that extracellular nucleotides contribute to the control of adult neurogenesis. Using immunocytochemistry, RT-PCR and western blotting, expression of both NTPDase2 and TNAP...
Journal Articles
Journal: Development
Development (2003) 130 (2): 391–399.
Published: 15 January 2003
...Gerd Kempermann; Daniela Gast; Golo Kronenberg; Masahiro Yamaguchi; Fred H. Gage New neurons are continually generated in the adult hippocampus, but the important question, whether adult neurogenesis is transient or leads to the lasting presence of new neurons, has not yet been answered. Dividing...