... Midline mutant Adaxial cells dzip1 PEST sequence Zebrafish During animal development, cell fates are specified in response to gradients of signaling molecules within the embryo. Members of the Hedgehog(Hh) family of intercellular signaling molecules control a variety of developmental...

... migration Convergence extension Adaxial cells Slow muscle Sclerotome Germ cells Metastasis Zebrafish Hyaluronan (HA) is a linear polysaccharide of high molecular weight,consisting of glucuronic acid (GlcA) and N -acetyl-glucosamine(GlcNAc) disaccharide repeats, linked by alternating β1-3...

... that zebrafish Gli1 is an activator of Hh-regulated genes, while zebrafish Gli2 has minor roles as a repressor or activator of Hh targets. * Author for correspondence (e-mail: [email protected] ) 14 11 2002 © 2003. 2003 Forebrain patterning Hedgehog signaling Adaxial cells floor...

... shows that diwanka gene activity is required in a small set of myotomal cells, called adaxial cells. We identified a subset of the adaxial cells to be sufficient to rescue the diwanka motor axon defect. Moreover, we show that this subset of adaxial cells delineates the common axonal path prior...

... somites is abnormal. In the second group of mutants, formation of the horizontal myoseptum, which separates the dorsal and ventral part of the myotome, is reduced. Six genes have been defined in this group ( you -type genes). you-too mutants show the most severe phenotype; in these the adaxial cells...