1-19 of 19
Keywords: Actomyosin
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2023) 150 (7): dev201238.
Published: 3 April 2023
... or encircled by supracellular actomyosin cables, junctional actomyosin enrichments networked between many neighbouring cells. We show that the single Drosophila Alp/Enigma-family protein Zasp52, which is most prominently found in Z-discs of muscles, is a component of many supracellular actomyosin structures...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2023) 150 (6): dev201099.
Published: 23 March 2023
... regulators with their physiological function. Here, we report an in vivo role of the actin-capping protein CAP-1 in the Caenorhabditis elegans germline. We show that CAP-1 is associated with actomyosin structures in the cortex and rachis, and its depletion or overexpression led to severe structural defects...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (15): dev200519.
Published: 11 August 2022
...Vishakha Vishwakarma; Thao Phuong Le; SeYeon Chung ABSTRACT Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate the cellular forces that drive cell shape changes and rearrangement. Rho1 signaling is activated by G-protein-coupled receptor (GPCR) signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (10): dev200181.
Published: 26 May 2022
... markers, suggesting that migration is concomitant with differentiation. Live imaging reveals anisotropic actomyosin contractility within epithelial trails, and genetic ablation of actomyosin contractility results in dispersion of epithelial collectives and failure of normal MES migration. These findings...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev199633.
Published: 21 July 2021
...Jack Bauer; Vincent Poupart; Eugénie Goupil; Ken C. Q. Nguyen; David H. Hall; Jean-Claude Labbé ABSTRACT The C. elegans germline is organized as a syncytium in which each germ cell possesses an intercellular bridge that is maintained by a stable actomyosin ring and connected to a common pool...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2021) 148 (11): dev199232.
Published: 14 June 2021
... of the ventral furrow. Actomyosin Morphogenesis RhoGAP RhoGEF Tissue folding Transcriptional patterning Drosophila National Institutes of General Medical Sciences R01GM125646 Alexander von Humboldt-Stiftung Massachusetts Institute of Technology http://dx.doi.org...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (9): dev193755.
Published: 7 May 2021
... of order/disorder as well as symmetry/asymmetry, revealing developmental instabilities that are part of normal morphogenesis. Craniofacial Avian embryo Frontonasal Fluctuating asymmetry Mathematical analysis Live cell imaging Organ culture Actomyosin Facial morphogenesis requires...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (4): dev194787.
Published: 15 February 2021
... actomyosin and stabilizing the adherens junction complex, including merlin. This leads to the cytoplasmic retention of YAP/TAZ to attenuate cell proliferation. These results shed light on the biological significance of blood-vessel geometry and the signaling mechanism through microenvironmental O 2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (22): dev174565.
Published: 21 November 2019
... of the cortical actomyosin network, and breaks symmetry to direct partitioning of the PAR proteins. However, the molecular nature of the centrosomal signal that triggers cortical anisotropy in the actomyosin network to promote polarity establishment remains elusive. Here, we discover that depletion of Aurora...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (13): dev174961.
Published: 4 July 2019
.... Using a zebrafish model and a combination of genetic tools, pharmacological agents and quantitative in vivo imaging, we reveal that a coordinated collective movement of DP cells drives PE formation. We found that Bmp signaling and the actomyosin cytoskeleton promote constriction of the DP, which enables...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (7): dev152488.
Published: 29 March 2018
... by actomyosin-based oriented cell rearrangement and resulting dynamic tissue reshaping (convergent extension, CE). By labeling clusters of cells spanning the entire heart primordia, we show that the heart primordia converge toward the midline to form a narrow tube, while extending perpendicularly to rapidly...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (5): dev149823.
Published: 8 March 2018
... expression, mislocalized actomyosin activity and increased cardiomyocyte proliferation that was dependent on Yap activity. To assess effects on tension, cardiomyocytes were cultured on deformable polyacrylamide hydrogels of varying stiffness. When grown on a stiff substrate, DKO cardiomyocytes exhibited...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (24): 4676–4686.
Published: 15 December 2016
...Julia Duque; Nicole Gorfinkiel In this work, we combine genetic perturbation, time-lapse imaging and quantitative image analysis to investigate how pulsatile actomyosin contractility drives cell oscillations, apical cell contraction and tissue closure during morphogenesis of the amnioserosa...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (10): 1794–1805.
Published: 15 May 2015
... ). Septins regulate the contractility of the actomyosin ring to enable adherens junction remodeling during cytokinesis of epithelial cells . Dev. Cell 24 , 242 - 255 . 10.1016/j.devcel.2013.01.008 Fox , D. T. , Gall , J. G. and Spradling , A. C. ( 2010 ). Error-prone polyploid...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1639–1650.
Published: 1 May 2015
... in the transverse plane, allowing sufficient time for lumen growth via an osmotic process along the longitudinal dimension. The dynamics of lumen formation is controlled by the TGFβ pathway and ROCK activity. Our findings reveal a TGFβ-ROCK-actomyosin contractility axis that coordinates lumen growth, which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3803–3812.
Published: 1 September 2011
... in Drosophila , and cells mutant for ed sort out from the surrounding wild-type cells. However, it remains unknown which factors trigger cell sorting. Here, we dissect the sequence of this process and find that cell sorting occurs when differential expression of Ed triggers the assembly of actomyosin cable...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (8): 1631–1641.
Published: 15 April 2011
.... Discontinuous localization of myosin II in the constriction indicates that the actomyosin network produces local contractions along the circumference. This reveals basal constriction by the actomyosin network as a novel mechanism for cell elongation. Following elongation, the notochord cells undergo...
Includes: Multimedia, Supplementary data