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Keywords: Actin
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2022) 149 (23): dev201214.
Published: 5 December 2022
...Koichi Hasegawa; Takeshi K. Matsui; Junpei Kondo; Ken-ichiro Kuwako ABSTRACT During neural development, the actin filament network must be precisely regulated to form elaborate neurite structures. N-WASP tightly controls actin polymerization dynamics by activating an actin nucleator Arp2/3. However...
Includes: Supplementary data
Journal Articles
In collection:
Plant development
Journal: Development
Development (2022) 149 (12): dev200415.
Published: 21 June 2022
... the importance of the cytoskeleton, including actin filaments and microtubules, in rice development and environmental responses. Yet, reliable in vivo cytoskeleton markers are lacking in rice, which limits our knowledge of cytoskeletal functions in living cells. Therefore, we generated bright fluorescent marker...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2020) 147 (17): dev186502.
Published: 2 September 2020
... changes. (A) Remodeling of the actin cortex enforces new cell-shape changes after Myosin II-driven cell-shape changes. During this process, primary actin filaments (red) are disassembled and then re-form (blue) to take on the shape of the new cell topology. (B) Endocytic pathways can direct the uptake...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2020) 147 (14): dev179168.
Published: 31 July 2020
... crossover between sister PVD dendrites. Our genetic analysis suggests that FMI-1 promotes transient F-actin assembly at the tips of contacting sister dendrites to facilitate their efficient retraction during self-avoidance events, probably by interacting with WSP-1/N-WASP. Mutations of vang-1 , which...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2019) 146 (7): dev164129.
Published: 4 April 2019
...Ashley A. DeAguero; Lizzet Castillo; Sandy T. Oas; Kaveh Kiani; Anton L. Bryantsev; Richard M. Cripps ABSTRACT Serum response factor (SRF) has an established role in controlling actin homeostasis in mammalian cells, yet its role in non-vertebrate muscle development has remained enigmatic. Here, we...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (7): dev171397.
Published: 4 April 2019
... of a dynamic filopodium-like branchlet. The mechanisms underlying the initiation of dendrite branchlets are therefore crucial to the shaping of dendrites. Through in vivo time-lapse imaging of the subcellular localization of actin during the process of branching of Drosophila larva sensory neurons, combined...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (24): dev168922.
Published: 12 December 2018
... by RhoGAP-mediated exclusion of PAR-6 from cell contacts . Science   320 , 1771 - 1774 . 10.1126/science.1156063 Barmich , M. J. , Rogers , S. and Häcker , U. ( 2005 ). DRhoGEF2 regulates actin organization and contractility in the Drosophila blastoderm embryo . J. Cell Biol.   168...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (14): dev161117.
Published: 30 July 2018
... and to specifically decipher the mechanisms controlling collective cell migration. Here, we identify the Drosophila Insulin/Insulin-like growth factor signalling (IIS) pathway as a key regulator in controlling actin dynamics in border cells, independently of its function in growth control. Loss of IIS activity blocks...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2017) 144 (23): 4249–4260.
Published: 1 December 2017
... 2017 http://www.biologists.com/user-licence-1-1/ Summary: This Review emphasizes the role of the actomyosin meshwork in determining the forces that operate within and between cells and their environment to shape and organize cells and tissues. Actin Contractility Morphogenesis...
Journal Articles
Journal: Development
Development (2016) 143 (20): 3806–3816.
Published: 15 October 2016
... is associated with diseases including cancer. However, how the undesired activation of PKC is prevented during development remains poorly understood. We have previously shown that a protein kinase, IKKε, is active at the growing bristle tip and regulates actin bundle organization during Drosophila bristle...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (15): 2741–2752.
Published: 1 August 2016
... development. However, the cytoskeletal mechanisms that drive radial glial outgrowth and maintain RGC polarity remain poorly understood. Here, we show that the Arp2/3 complex – the unique actin nucleator that produces branched actin networks – plays essential roles in RGC polarity and morphogenesis. Disruption...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (23): 4107–4118.
Published: 1 December 2015
... is responsible for mediating RC tyrosine phosphorylation, and loss of Src64 causes a reduction in RC diameter within germline cysts. Mechanistically, we show that Src64 controls an actin network around the RCs that depends on Abl and the Rac/SCAR/Arp2/3 pathway. The actin network around RCs is required...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (14): 2478–2486.
Published: 15 July 2015
... of distally pointing cuticular hairs. Using in vivo imaging we found that, early in hair growth, cells have multiple actin bundles and hairs that subsequently fuse into a single growing hair. The downstream PCP gene multiple wing hairs ( mwh ) plays a key role in this process and acts to antagonize the actin...
Includes: Supplementary data