... from the Joint Genome Institute (JGI) and the annotated protein ID 233300 for amphioxus Achaete-scute homolog gene product (Satou et al., 2008), a pair of Achaete-scute homolog specific primers were designed, and Bam HI and Eco RI restriction enzyme sites were added to their 5′ ends, respectively...

...Michael J. Layden; Michiel Boekhout; Mark Q. Martindale achaete-scute homologs (ash) regulate neural development in all bilaterian model animals indicating that they represent a component of the ancestral neurogenic pathway. We test this by investigating four ash genes during development of a basal...

...Luc Vanolst; Catherine Fromental-Ramain; Philippe Ramain The GATA factor Pannier (Pnr) activates proneural expression through binding to a remote enhancer of the achaete-scute (ac-sc)complex. Chip associates both with Pnr and with the (Ac-Sc)-Daughterless heterodimer bound to the ac-sc promoters...

... differentiation pathway, starting at the level of interstitial stem cells. Expression of Hyzic is restricted to the proliferative stages of nematoblasts. Hyzic acts before and possibly directly upstream of Cnash , a homolog of the proneural bHLH transcription factor gene achaete-scute , and of Nowa , an early...

...Scott R. Wheeler; Michelle L. Carrico; Beth A. Wilson; Susan J. Brown; James B. Skeath The study of achaete-scute (ac/sc) genes has recently become a paradigm to understand the evolution and development of the arthropod nervous system. We describe the identification and characterization of the ac...

.... Cell Dev. Biol. 16, 243-271). It specifies pattern in the dorsal body. On the dorsal notum it is expressed in a broad medial domain and directly regulates transcription of the achaete-scute (ac-sc) genes driving their expression in small discrete clusters within this domain at the sites of each future...

...Daniela Pistillo; Nick Skaer; Pat Simpson In Drosophila the stereotyped arrangement of sensory bristles on the notum is determined by the tightly regulated control of transcription of the achaete-scute (ac-sc) genes which are expressed in small proneural clusters of cells at the sites of each...

...Corinna Wülbeck; Pat Simpson ABSTRACT The stereotyped positioning of sensory bristles in Drosophila has been shown to result from complex spatiotemporal regulation of the proneural achaete-scute genes, that relies on an array of cis- regulatory elements and spatially restricted transcriptional...

.... Thus, Wingless has only a permissive role on dorsocentral achaete-scute expression. We also provide evidence indicating that Pannier and U-shaped are main effectors of the regulation of wingless expression in the presumptive notum. In contrast, other data suggest that Pnr represses wg . Thus...

...Makoto Sato; Tetsuya Kojima; Tatsuo Michiue; Kaoru Saigo In Drosophila notum, the expression of achaete-scute proneural genes and bristle formation have been shown to be regulated by putative prepattern genes expressed longitudinally. Here, we show that two homeobox genes at the Bar locus (BarH1...

...Ann Grens; Elizabeth Mason; J. Lawrence Marsh; Hans R. Bode ABSTRACT Members of the Achaete-scute family of basic helix-loophelix transcription factors are involved in cell fate specification in vertebrates and invertebrates. We have isolated and characterized a cnidarian achaete-scute homolog...

...Carlos V. Cabrera; María C. Alonso; Hella Huikeshoven ABSTRACT The pattern of adult sensilla in Drosophila is established by the dosage-sensitive interaction of two antagonistic groups of genes. Sensilla development is promoted by members of the achaete - scute complex and the daughterless gene...

...Harald Vaessin; Michael Brand; Lily Yeh Jan; Yuh Nung Jan ABSTRACT The first steps of neuronal precursor formation require several genes that encode transcription regulators with the helix-loop-helix (HLH) motif, including the proneural genes of the achaete-scute complex AS-C (achaete (ac), scute...

...Kathryn Zimmerman; John Shih; Julie Bars; Andres Collazo; David J. Anderson ABSTRACT We have isolated a novel Xenopus homolog of the Drosophila achaete-scute genes, called XASH-3. XASH-3 expression is neural specific and is detected as early as stage 11, making it one of the earliest markers...

...Carlos V. Cabrera * We are sad to inform readers that Carlos Cabrera died on April 10th 1992 at the early age of 41. 01 04 1992 © 1992 by Company of Biologists 1992 Drosophila neurogenesis achaete-scute cell lineage cell interactions During animal...

...Jane E. Johnson; Kathryn Zimmerman; Tetsuichiro Saito; David J. Anderson ABSTRACT MASH1 and MASH2, mammalian homologues of the Drosophila neural determination genes achaete-scute , are members of the basic helix-loop-helix (bHLH) family of transcription factors. We show here that murine P19...