...)-expressing neuroblasts undergo apoptosis in females whereas their male counterparts proliferate and give rise to serotonergic neurons crucial for adult mating behaviour. Our study demonstrates that the female-specific isoform of Dsx collaborates with Hox gene Abdominal-B ( Abd-B ) to bring about...

... and anterior abdominal neuromeres are almost equally sized and formed by repetitive sets of neuroblasts, whereas the terminal abdominal neuromeres are generated by significantly smaller populations of progenitor cells. Here we investigated the role of the Hox gene Abdominal-B in shaping the terminal neuromeres...

.... Promoter competition and insulators are thought to play a role in regulating these interactions. In the bithorax complex of Drosophila , the IAB5 enhancer is located 55 kb 3′ of the Abdominal-B ( Abd-B ) promoter and 48 kb 5′ of the abdominal-A ( abd-A ) promoter. Although roughly equidistant from the two...

...David Foronda; Beatriz Estrada; Luis de Navas; Ernesto Sánchez-Herrero The genitalia of Drosophila derive from the genital disc and require the activity of the Abdominal-B ( Abd-B ) Hox gene. This gene encodes two different proteins, Abd-B M and Abd-B R. We show here that the embryonic genital...

...Qing Lin; Di Wu; Jumin Zhou Transcriptional enhancers in large gene complexes activate promoters over huge distances, yet little is known about the mechanism of these long-range interactions. We report that the promoter targeting sequence (PTS) from the Abdominal-B locus of the Drosophila bithorax...

.... The Abdominal-B Hox gene of the bithorax complex of Drosophila is regulated by several infraabdominal domains,which determine Abdominal-B expression in abdominal segments A5 to A9(parasegments 10 to 14). Some of the infraabdominal domains have been characterized, including an infraabdominal -8 domain, which has...

... for correspondence (e-mail: kaufman@bio.indiana.edu ) 12 12 2001 © 2002. 2002 Body plan Centipede Chilopoda Lithobius Hox labial proboscipedia Hox3 Deformed Sex combs reduced fushi tarazu Antennapedia Ultrabithorax abdominal-A Abdominal-B Over 500...

...Beatriz Estrada; Ernesto Sánchez-Herrero ABSTRACT In Drosophila , the Hox gene Abdominal-B is required to specify the posterior abdomen and the genitalia. Homologues of Abdominal-B in other species are also needed to determine the posterior part of the body. We have studied the function...

... is to pattern the realization of this capability. * Author for correspondence (e-mail: emmons@aecom.yu.edu ) 24 11 1999 05 10 1999 © 1999 by Company of Biologists 1999 TGFβ dpp BMP Hox gene Abdominal-B Dopamine Neurotransmitter Neuron identity Caenorhabditis elegans...

... of Biologists 1998 Ultrabithorax abdominal-A Abdominal-B Trans -sensing Chromosome painting Homologous pairing CLSM FISH Pairing of homologous chromosomes in Diptera like Drosophila has been inferred from physical observations made in the early part of this century on the close...

... proteins that have been suggested to form heterochromatin-like structures. By studying the expression of reporter genes, we have identified a 725 bp fragment, called MCP725, in the homeotic gene Abdominal-B , that accurately maintains position-specific silencing during proliferation of imaginal cells...

...Aihua Zhu; Michael A. Kuziora ABSTRACT A chimeric protein consisting of Deformed with a substituted Abdominal-B homeodomain (Dfd/Abd-B) is used to identify protein domains outside the homeodomain that are required for regulatory activity in vivo. A series of deletion proteins were generated based...

... proteins for the regulation of their down-stream targets. * Author for correspondence † Present address: Sanger Centre, Hinxton Hall, Cambridge CB10 1RQ, UK 05 04 1994 © 1994 by Company of Biologists 1994 Ultrabithorax abdominal-A Abdominal-B bithorax complex GAL4...

...Robert Kelsh; Iain Dawson; Michael Akam ABSTRACT We have cloned a homologue of the homeotic gene Abdominal-B from the locust Schistocerca gregaria and raised antibodies against the homeodomain and C-terminal flanking region of the encoded protein. This antibody stains the posterior abdomen...

...Michele L. Lamka; Anne M. Boulet; Shigeru Sakonju ABSTRACT The Abdominal-B ( Abd-B ) gene, a member of the bithorax complex (BX-C), specifies the identities of parasegments (PS) 10-14 in Drosophila. Abd-B codes for two structurally related homeodomain proteins, ABD-B m and ABD-B r...

... to analyze the structural changes in the E complex mutations. We used three newly isolated Bombyx homeobox genes as probes. These genes are probably homologues of the Ultrabiihorax (Ubx), ab-dominal-A (abd-A) and Abdominal-B (Abd-B) in the Drosophila bithorax complex, because the amino-acid sequences...

...Anne M. Boulet; Alan Lloyd; Shigeru Sakonju The Abdominal-B (Abd-B) gene, a member of the Drosophila bithorax complex, is required during development to specify the identity of parasegments 10– 14. Based on genetic studies, Casanova, J., Sánchez-Herrero, E. and Morata, G. (1986) Cell 47, 627-636...

...Mauro Delorenzi; Mariann Bienz The Abdominal-B (Abd-B) gene determines development of the posteriormost segments in Drosophila . Genetic and molecular analysis suggested that it consists of two genetically separable functions that are conferred by two related homeoproteins termed m and r. We have...

...Jordi Casanova; Robert A. H. White ABSTRACT We have investigated the functional organization of the Abdominal-B gene in the bithorax complex using the expression of the Ultrabithorax gene as an assay for Abdominal-B trans-regulatory functions. Using Polycomb mutants to relax the normal spatial...