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Keywords: ATP
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Journal Articles
Journal: Development
Development (2012) 139 (1): 215–224.
Published: 01 January 2012
... we characterise the signalling pathway of extracellular Engrailed. Our results show that Engrailed/ephrin A5 synergy in growth cone collapse involves adenosine A1 receptor activation after Engrailed-dependent ATP synthesis, followed by ATP secretion and hydrolysis to adenosine. This is, to our...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (4): 675–684.
Published: 15 February 2006
... and investigated their functional properties in vitro. Neurospheres cultured from the adult mouse SVZ in the presence of epidermal growth factor and fibroblast growth factor 2 expressed the ecto-nucleotidases NTPDase2 and the tissue non-specific isoform of alkaline phosphatase, hydrolyzing extracellular ATP...
Journal Articles
Journal: Development
Development (2005) 132 (12): 2873–2882.
Published: 15 June 2005
.... Investigating the regulation of cell number in the retina we found an ATP gated mechanism of neuronal death control. By degrading endogenous extracellular ATP or blocking the P2X 7 ATP receptors we found that endogenous extracellular ATP triggers the death of retinal cholinergic neurons during normal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (4): 683–692.
Published: 15 February 2003
...+ wave pacemaker PM2 can be restored or stimulated by flash photolysis of caged ATP. Taken together our observations provide the first evidence that, in addition to buffering cytosolic Ca 2+ , the egg's mitochondria are stimulated by Ins(1,4,5) P 3 -mediated Ca 2+ signals. In turn,mitochondrial ATP...
Journal Articles
Journal: Development
Development (1986) 93 (1): 73–84.
Published: 01 April 1986
... to be metabolically active for expression of the force. This contention was demonstrated using an in vitro system that allows substantial reorientation of the hard palate to occur. ATP levels were reduced by treatment with metabolic inhibitors and the degree of reorientation was measured 1 h following pretreatment...