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Keywords: APRIN
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Journal Articles
Bin Zhang, Sanjay Jain, Haengseok Song, Ming Fu, Robert O. Heuckeroth, Jonathan M. Erlich, Patrick Y. Jay, Jeffrey Milbrandt
Journal:
Development
Development (2007) 134 (17): 3191–3201.
Published: 1 September 2007
... are associated with the developmental disorder Cornelia de Lange syndrome (CdLS) in humans. To delineate the physiological roles of PDS5B in mammals, we generated mice lacking PDS5B (APRIN). Pds5B- deficient mice died shortly after birth. They exhibited multiple congenital anomalies,including heart defects...
Includes: Supplementary data