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Keywords: APP
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Journal Articles
Journal: Development
Development (2017) 144 (15): 2730–2736.
Published: 1 August 2017
... cell (NSC) quiescence and growth. Here, we have uncovered a role for soluble amyloid precursor protein (sAPP) as a vascular niche signal in the subventricular zone (SVZ) of the lateral ventricle of the adult mouse brain. sAPP suppresses NSC growth in culture. Further in vivo studies on the role of APP...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (21): 3986–3996.
Published: 1 November 2012
... that amyloid precursor protein (APP) plays a role in migration into the cortical plate through its interaction with two cytosolic signaling proteins, disabled 1 (DAB1) and disrupted in schizophrenia 1 (DISC1). In order to identify extracellular factors that may signal through APP to regulate migration, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (9): 2173–2181.
Published: 1 May 2004
...Isabelle Caillé; Bernadette Allinquant; Edmond Dupont; Colette Bouillot; Andreas Langer; Ulrike Müller; Alain Prochiantz The amyloid precursor protein (APP) is a type I transmembrane protein of unknown physiological function. Its soluble secreted form (sAPP) shows similarities with growth factors...