... homeodomain and a YPWM motif, situated amino terminally to it. Despite their highly diverse functions in vivo, HOX proteins display similar biochemical properties in vitro, raising the question of how this specificity is achieved. In our study, we investigated the importance of the Antennapedia ( Antp ) YPWM...

... Krüppel Giant Even-skipped Dfd Scr Antp Ubx Short germ Long germ segmentation Gap gene Abdomen Jaws Tribolium castaneum Drosophila Evolution Parental RNAi Anteroposterior patterning in Drosophila is controlled by regulatory elements that measure the local...

... 11 1999 21 09 1999 © 1999 by Company of Biologists 1999 split ends (spen) Hox RNA binding Drosophila melanogaster Antp Repressor The homeotic genes in Drosophila can be divided into three classes: (1) genes of the homeotic selector, or Hox class, which...

... of the posterior head and thorax. Genes encoding chimeric Antp/Scr proteins were introduced into flies and their effects on morphology and target gene regulation observed. We find that the N terminus of the homeodomain is critical for determining the specific effects of these homeotic proteins in vivo, but other...