...Kenya Imaimatsu; Ryuji Hiramatsu; Ayako Tomita; Hirotsugu Itabashi; Yoshiakira Kanai ABSTRACT Temporal transcription profiles of fetal testes with Sertoli cell ablation were examined in 4-day culture using a diphtheria toxin (DT)-dependent cell knockout system in AMH- TRECK transgenic (Tg) mice...

... receptor 1, activated by estrogen, binds to the 5′ region of the anti-Mullerian hormone ( Amh ) gene and upregulates its transcription before follicle formation in cultured mouse fetal ovaries. Ectopic expression of AMH protein was observed in pregranulosa cells of these explants. Furthermore, the addition...

...Shuhei Nakamura; Ikuko Watakabe; Toshiya Nishimura; Jean-Yves Picard; Atsushi Toyoda; Yoshihito Taniguchi; Nathalie di Clemente; Minoru Tanaka The function of AMH (Anti-Müllerian hormone), a phylogenetically ancient member of the TGFβ family of proteins, in lower vertebrates is largely unknown...

...Akio Kobayashi; C. Allison Stewart; Ying Wang; Kaoru Fujioka; Nicholas C. Thomas; Soazik P. Jamin; Richard R. Behringer During male sexual differentiation, the transforming growth factor-β (TGF-β) signaling molecule anti-Müllerian hormone (AMH; also known as Müllerian inhibiting substance, MIS...

... is correlated with a cranial to caudal gradient of anti-Müllerian hormone receptor protein, followed by a wave of apoptosis spreading along the Müllerian duct as its progresses caudally. Apoptosis is also induced by AMH in female Müllerian duct in vitro. Furthermore, apoptotic indexes are increased in Müllerian...