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Keywords: ADAM
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Journal Articles
Journal: Development
Development (2012) 139 (20): 3693–3709.
Published: 15 October 2012
...Silvio Weber; Paul Saftig Proteolytic enzymes belonging to the A Disintegin And Metalloproteinase (ADAM) family are able to cleave transmembrane proteins close to the cell surface, in a process referred to as ectodomain shedding. Substrates for ADAMs include growth factors, cytokines, chemokines...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (10): 2381–2389.
Published: 15 May 2002
... the ability of ampA null cells to fill this role. Thus, in spite of its simpler structure, the Dictyostelium ampA protein carries out the same diversity of functions that have been observed for the ADAM and ADAMTS families in metazoans. Like the multi-domain ADAM and ADAMTS proteins of higher metazoans...