... growth in Bombyx by directly regulating the ecdysteriod biosynthesis enzyme gene ( shade ) in the wing tissue, which leads to local production of the growth hormone 20-hydroxyecdysone . Additional targets of Antp are wing cuticular protein genes CPG24 , CPH28 and CPG9 , which are essential for wing...

... of the JH-deficient animals, Dronc and Drice ,two caspase genes that are crucial for PCD induced by the molting hormone 20-hydroxyecdysone (20E), were significantly upregulated. These results demonstrated that JH antagonizes 20E-induced PCD by restricting the mRNA levels of Dronc and Drice...

...David T. Champlin; James W. Truman ABSTRACT The eye primordium of the moth, Manduca sexta , shows two different developmental responses to ecdysteroids depending on the concentration to which it is exposed. Tonic exposure to moderate levels of 20-hydroxyecdysone (20E) or its precursor, ecdysone...

... and maturational responses to ecdysteroids by requiring tonic exposure to the hormone and lower levels of 20-hydroxyecdysone, and by being sensitive to either 20-hydroxyecdysone or its precursor, ecdysone. These characteristics allow optic lobe development to be divided into two ecdysteroid-dependent phases...

... minutes to about 1.75 hours post-emergence. Fig. 6. 20-HE treatment blocks the death of the type II neurons. (A,C) A montage of the dorsal aspect of immunoperoxidase-stained nervous systems showing the effects of 20-hydroxyecdysone (20-HE) treatment on the survival of the EcR-A hyperexpressing...

...Mary Bownes; Ann Scott; Mairead Blair ABSTRACT The three yolk-protein genes of Drosophila are normally expressed only in adult female fat bodies and ovaries. 20-hydroxyecdysone can affect the transcription of these genes in males and females, as can mutations in the sex-determining genes tra, tra-2...