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Keywords: δ cell specification
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Journal Articles

Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification

David S. Lorberbaum, Siddharth Kishore, Carolina Rosselot, Dylan Sarbaugh, Elliott P. Brooks, Eloise Aragon, Shouhong Xuan, Olivier Simon, Debashis Ghosh, Cathy Mendelsohn, Paul Gadue, Lori Sussel
Journal: Development
Development (2020) 147 (12): dev189977.
https://doi.org/10.1242/dev.189977
Published: 22 June 2020
.... β cell differentiation Retinoic acid signaling Wnt signaling Pancreas development Diabetes δ cell specification Cell signaling pathways are used continuously throughout development and adulthood to mediate tissue interactions and precisely control gene expression. In particular...
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Includes: Supplementary data