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Keywords: β-Cell proliferation
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Journal Articles
Journal: Development
Development (2021) 148 (16): dev194928.
Published: 16 August 2021
... or glucose tolerance. As TRPM7 regulates cell proliferation, we assessed how TRPM7 influences β-cell hyperplasia under insulin-resistant conditions. β-Cell proliferation induced by high-fat diet was significantly decreased in TRPM7-deficient β-cells. The endocrine roles of TRPM7 may be influenced by cation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (21): 3637–3648.
Published: 01 November 2015
... acts as a lineage specification factor in the mouse pancreas – promoting beta-cell fate and maintenance. It also has a role in compensatory beta-cell proliferation. β-cell versus δ-cell fate selection Endocrine lineage diversification β-cell fate maintenance β-cell proliferation Islet...
Includes: Supplementary data