... to propose that one role of Syph is to coordinate the actin and MT networks during filopodial dynamics through differential cargo transport. Consistent with this possibility, we find that both α-tubulin and actin overexpression rescues the Syph `failure to close' phenotype, and in the case of actin...

... bodies. An α-tubulin gene was isolated and characterized. A lacZ fusion gene under control of the 5′ upstream region of this tubulin gene was microinjected into embryos at the two-cell stage. The reporter gene product was only detected in the three trochoblast cell-lines at the same time as tubulin genes...