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Journal Articles

The unique functions of Runx1 in skeletal muscle maintenance and regeneration are facilitated by an ETS interaction domain

In collection:

Chromatin and epigenetics

Meng Yu, Konrad Thorner, Sreeja Parameswaran, Wei Wei, Chuyue Yu, Xinhua Lin, Raphael Kopan, Matthew R. Hass

Development (2024) 151 (24): dev202556.

https://doi.org/10.1242/dev.202556

Published: 12 December 2024

View article titled, The unique functions of Runx1 in skeletal muscle maintenance and regeneration are facilitated by an ETS interaction domain

Includes: Supplementary data

Journal Articles

Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis

Kathryn Duvall, Lauren Crist, Alison J. Perl, Naomi Pode Shakked, Praneet Chaturvedi, Raphael Kopan

Development (2022) 149 (10): dev200446.

https://doi.org/10.1242/dev.200446

Published: 16 May 2022

View article titled, Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis

Includes: Supplementary data

Journal Articles

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

Zhenyi Liu, Eric Brunskill, Barbara Varnum-Finney, Chi Zhang, Andrew Zhang, Patrick Y. Jay, Irv Bernstein, Mitsuru Morimoto, Raphael Kopan

Development (2015) 142 (14): 2452–2463.

https://doi.org/10.1242/dev.125492

Published: 15 July 2015

View article titled, The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

Includes: Supplementary data

Journal Articles

Second-generation Notch1 activity-trap mouse line (N1IP::Cre HI ) provides a more comprehensive map of cells experiencing Notch1 activity

Zhenyi Liu, Eric Brunskill, Scott Boyle, Shuang Chen, Mustafa Turkoz, Yuxuan Guo, Rachel Grant, Raphael Kopan

Development (2015) 142 (6): 1193–1202.

https://doi.org/10.1242/dev.119529

Published: 15 March 2015

View article titled, Second-generation Notch1 activity-trap mouse line (N1IP::Cre HI ) provides a more comprehensive map of cells experiencing Notch1 activity

Includes: Supplementary data

Journal Articles

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development

Scott C. Boyle, Zhenyi Liu, Raphael Kopan

Development (2014) 141 (2): 346–354.

https://doi.org/10.1242/dev.100271

Published: 15 January 2014

View article titled, Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development

Includes: Supplementary data

Journal Articles

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

Mitsuru Morimoto, Ryuichi Nishinakamura, Yumiko Saga, Raphael Kopan

Development (2012) 139 (23): 4365–4373.

https://doi.org/10.1242/dev.083840

Published: 1 December 2012

View article titled, Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

Includes: Supplementary data

Journal Articles

Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells

Scott C. Boyle, Mijin Kim, M. Todd Valerius, Andrew P. McMahon, Raphael Kopan

Development (2011) 138 (19): 4245–4254.

https://doi.org/10.1242/dev.070433

Published: 1 October 2011

View article titled, Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells

Includes: Supplementary data

Journal Articles

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

Mitsuru Morimoto, Zhenyi Liu, Hui-Teng Cheng, Niki Winters, David Bader, Raphael Kopan

Development (2010) 137 (3): e1.

https://doi.org/10.1242/dev.048249

Published: 1 February 2010

View article titled, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

Journal Articles

Notch signaling in bulge stem cells is not required for selection of hair follicle fate

Shadmehr Demehri, Raphael Kopan

Development (2009) 136 (6): 891–896.

https://doi.org/10.1242/dev.030700

Published: 15 March 2009

View article titled, Notch signaling in bulge stem cells is not required for selection of hair follicle fate

Includes: Supplementary data

Journal Articles

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron

Hui-Teng Cheng, Mijin Kim, M. Todd Valerius, Kameswaran Surendran, Karin Schuster-Gossler, Achim Gossler, Andrew P. McMahon, Raphael Kopan

Development (2007) 134 (24): 4506.

https://doi.org/10.1242/dev.02887

Published: 15 December 2007

View article titled, Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron

Journal Articles

Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes

Jonghyeob Lee, Jacob M. Basak, Shadmehr Demehri, Raphael Kopan

Development (2007) 134 (15): 2795–2806.

https://doi.org/10.1242/dev.02868

Published: 1 August 2007

View article titled, Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes

Includes: Supplementary data

Journal Articles

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron

Hui-Teng Cheng, Mijin Kim, M. Todd Valerius, Kameswaran Surendran, Karin Schuster-Gossler, Achim Gossler, Andrew P. McMahon, Raphael Kopan

Development (2007) 134 (4): 801–811.

https://doi.org/10.1242/dev.02773

Published: 15 February 2007

View article titled, Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron

Includes: Supplementary data

Journal Articles

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

Marc Vooijs, Chin-Tong Ong, Brandon Hadland, Stacey Huppert, Zhenyi Liu, Jeroen Korving, Maaike van den Born, Thaddeus Stappenbeck, Yumei Wu, Hans Clevers, Raphael Kopan

Development (2007) 134 (3): 535–544.

https://doi.org/10.1242/dev.02733

Published: 1 February 2007

View article titled, Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

Includes: Supplementary data

Journal Articles

A garden of Notch-ly delights

Gerry Weinmaster, Raphael Kopan

Development (2006) 133 (17): 3277–3282.

https://doi.org/10.1242/dev.02515

Published: 1 September 2006

View article titled, A garden of Notch-ly delights

Journal Articles

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear

Amy E. Kiernan, Ralf Cordes, Raphael Kopan, Achim Gossler, Thomas Gridley

Development (2005) 132 (19): 4353–4362.

https://doi.org/10.1242/dev.02002

Published: 1 October 2005

View article titled, The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear

Journal Articles

γ-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

Hui-Teng Cheng, Jeffrey H. Miner, MeeiHua Lin, Malú G. Tansey, Kevin Roth, Raphael Kopan

Development (2003) 130 (20): 5031–5042.

https://doi.org/10.1242/dev.00697

Published: 15 October 2003

View article titled, γ-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

Journal Articles

Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers

Meei-Hua Lin, Cornelia Leimeister, Manfred Gessler, Raphael Kopan

Development (2000) 127 (11): 2421–2432.

https://doi.org/10.1242/dev.127.11.2421

Published: 1 June 2000

View article titled, Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers

Journal Articles

An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells

Jeffrey S. Nye, Raphael Kopan, Richard Axel

Development (1994) 120 (9): 2421–2430.

https://doi.org/10.1242/dev.120.9.2421

Published: 1 September 1994

View article titled, An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells

Journal Articles

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

Raphael Kopan, Jeffrey S. Nye, Harold Weintraub

Development (1994) 120 (9): 2385–2396.

https://doi.org/10.1242/dev.120.9.2385

Published: 1 September 1994

View article titled, The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

NARROW

The unique functions of Runx1 in skeletal muscle maintenance and regeneration are facilitated by an ETS interaction domain

Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

Second-generation Notch1 activity-trap mouse line (N1IP::Cre HI ) provides a more comprehensive map of cells experiencing Notch1 activity

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

Notch signaling in bulge stem cells is not required for selection of hair follicle fate

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron

Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

A garden of Notch-ly delights

The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear

γ-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers

An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

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