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James M. Wells
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Journal Articles

RFX6 regulates human intestinal patterning and function upstream of PDX1

J. Guillermo Sanchez, Scott Rankin, Emily Paul, Heather A. McCauley, Daniel O. Kechele, Jacob R. Enriquez, Nana-Hawa Jones, Siri A. W. Greeley, Lisa Letourneau-Freiberg, Aaron M. Zorn, Mansa Krishnamurthy, James M. Wells
Journal: Development
Development (2024) 151 (18): dev204379.
https://doi.org/10.1242/dev.204379
Published: 20 September 2024
View articletitled, RFX6 regulates human intestinal patterning and function upstream of PDX1
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Journal Articles

RFX6 regulates human intestinal patterning and function upstream of PDX1

J. Guillermo Sanchez, Scott Rankin, Emily Paul, Heather A. McCauley, Daniel O. Kechele, Jacob R. Enriquez, Nana-Hawa Jones, Siri A. W. Greeley, Lisa Letourneau-Freiberg, Aaron M. Zorn, Mansa Krishnamurthy, James M. Wells
Journal: Development
Development (2024) 151 (9): dev202529.
https://doi.org/10.1242/dev.202529
Published: 9 May 2024
View articletitled, RFX6 regulates human intestinal patterning and function upstream of PDX1
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Includes: Supplementary data
Journal Articles

Transplanted human intestinal organoids: a resource for modeling human intestinal development

Akaljot Singh, Holly M. Poling, Praneet Chaturvedi, Konrad Thorner, Nambirajan Sundaram, Daniel O. Kechele, Charlie J. Childs, Heather A. McCauley, Garrett W. Fisher, Nicole E. Brown, Jason R. Spence, James M. Wells, Michael A. Helmrath
Journal: Development
Development (2023) 150 (9): dev201416.
https://doi.org/10.1242/dev.201416
Published: 5 May 2023
View articletitled, Transplanted human intestinal organoids: a resource for modeling human intestinal development
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Includes: Supplementary data
Journal Articles

In preprints: humans, the new model organism

In collection:
In preprints
James M. Wells, Ziyuan Guo
Journal: Development
Development (2022) 149 (22): dev201395.
https://doi.org/10.1242/dev.201395
Published: 28 November 2022
View articletitled, In preprints: humans, the new model organism
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Journal Articles

A renaissance for developmental biology driven by new in vitro platforms

James M. Wells
Journal: Development
Development (2022) 149 (20): dev201365.
https://doi.org/10.1242/dev.201365
Published: 1 November 2022
View articletitled, A renaissance for developmental biology driven by new in vitro platforms
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Journal Articles

Deriving functional human enteroendocrine cells from pluripotent stem cells

Katie L. Sinagoga, Heather A. McCauley, Jorge O. Múnera, Nichole A. Reynolds, Jacob R. Enriquez, Carey Watson, Hsiu-Chiung Yang, Michael A. Helmrath, James M. Wells
Journal: Development
Development (2018) 145 (19): dev165795.
https://doi.org/10.1242/dev.165795
Published: 1 October 2018
View articletitled, Deriving functional human enteroendocrine cells from pluripotent stem cells
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Includes: Supplementary data
Journal Articles

Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets

Katie L. Sinagoga, William J. Stone, Jacqueline V. Schiesser, Jamie I. Schweitzer, Leesa Sampson, Yi Zheng, James M. Wells
Journal: Development
Development (2017) 144 (13): 2402–2414.
https://doi.org/10.1242/dev.146316
Published: 1 July 2017
View articletitled, Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets
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Includes: Supplementary data
Journal Articles

Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish

Heather A. McCauley, James M. Wells
Journal: Development
Development (2017) 144 (6): 958–962.
https://doi.org/10.1242/dev.140731
Published: 15 March 2017
View articletitled, Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish
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Includes: Supplementary data
Journal Articles

A process engineering approach to increase organoid yield

Natasha Arora, Jasmin Imran Alsous, Jacob W. Guggenheim, Michael Mak, Jorge Munera, James M. Wells, Roger D. Kamm, H. Harry Asada, Stanislav Y. Shvartsman, Linda G. Griffith
Journal: Development
Development (2017) 144 (6): 1128–1136.
https://doi.org/10.1242/dev.142919
Published: 15 March 2017
View articletitled, A process engineering approach to increase organoid yield
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Includes: Supplementary data
Journal Articles

How to make an intestine

James M. Wells, Jason R. Spence
Journal: Development
Series: Primer Series
Development (2014) 141 (4): 752–760.
https://doi.org/10.1242/dev.097386
Published: 15 February 2014
View articletitled, How to make an intestine
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Journal Articles

Klf5 regulates lineage formation in the pre-implantation mouse embryo

Suh-Chin J. Lin, Maqsood A. Wani, Jeffrey A. Whitsett, James M. Wells
Journal: Development
Development (2010) 137 (23): 3953–3963.
https://doi.org/10.1242/dev.054775
Published: 1 December 2010
View articletitled, Klf5 regulates lineage formation in the pre-implantation mouse embryo
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Includes: Supplementary data
Journal Articles

Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung

Amanda E. Serls, Shawna Doherty, Pankhuri Parvatiyar, James M. Wells, Gail H. Deutsch
Journal: Development
Development (2005) 132 (1): 35–47.
https://doi.org/10.1242/dev.01570
Published: 1 January 2005
View articletitled, Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
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Journal Articles

Global expression analysis of gene regulatory pathways during endocrine pancreatic development

Guoqiang Gu, James M. Wells, David Dombkowski, Fred Preffer, Bruce Aronow, Douglas A. Melton
Journal: Development
Development (2004) 131 (1): 165–179.
https://doi.org/10.1242/dev.00921
Published: 1 January 2004
View articletitled, Global expression analysis of gene regulatory pathways during endocrine pancreatic development
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Includes: Supplementary data
Journal Articles

Early mouse endoderm is patterned by soluble factors from adjacent germ layers

James M. Wells, Douglas A. Melton
Journal: Development
Development (2000) 127 (8): 1563–1572.
https://doi.org/10.1242/dev.127.8.1563
Published: 15 April 2000
View articletitled, Early mouse endoderm is patterned by soluble factors from adjacent germ layers
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Journal Articles

Aprotinin, a Kunitz-type protease inhibitor, stimulates skeletal muscle differentiation

James M. Wells, Sidney Strickland
Journal: Development
Development (1994) 120 (12): 3639–3647.
https://doi.org/10.1242/dev.120.12.3639
Published: 1 December 1994
View articletitled, Aprotinin, a Kunitz-type protease inhibitor, stimulates skeletal muscle differentiation
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Journal Articles

Preimplantation mouse embryos express a cell surface receptor for tissue-plasminogen activator

Pamela M. Carroll, William G. Richards, Andrew L. Darrow, James M. Wells, Sidney Strickland
Journal: Development
Development (1993) 119 (1): 191–198.
https://doi.org/10.1242/dev.119.1.191
Published: 1 September 1993
View articletitled, Preimplantation mouse embryos express a cell surface receptor for tissue-plasminogen activator
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