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Hitoshi Niwa
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Journal Articles

Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation

Sofiane Hamidi, Yukiko Nakaya, Hiroki Nagai, Cantas Alev, Takeya Kasukawa, Sapna Chhabra, Ruda Lee, Hitoshi Niwa, Aryeh Warmflash, Tatsuo Shibata, Guojun Sheng
Journal: Development
Development (2020) 147 (3): dev184960.
https://doi.org/10.1242/dev.184960
Published: 3 February 2020
View article titled, Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation
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Includes: Supplementary data
Journal Articles

Overlapping functions of Krüppel-like factor family members: targeting multiple transcription factors to maintain the naïve pluripotency of mouse embryonic stem cells

Mariko Yamane, Satoshi Ohtsuka, Kumi Matsuura, Akira Nakamura, Hitoshi Niwa
Journal: Development
Development (2018) 145 (10): dev162404.
https://doi.org/10.1242/dev.162404
Published: 30 May 2018
View article titled, Overlapping functions of Krüppel-like factor family members: targeting multiple transcription factors to maintain the naïve pluripotency of mouse embryonic stem cells
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Includes: Supplementary data
Journal Articles

The principles that govern transcription factor network functions in stem cells

Hitoshi Niwa
Journal: Development
Development (2018) 145 (6): dev157420.
https://doi.org/10.1242/dev.157420
Published: 14 March 2018
View article titled, The principles that govern transcription factor network functions in stem cells
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Journal Articles

The differential activation of intracellular signaling pathways confers the permissiveness of embryonic stem cell derivation from different mouse strains

Satoshi Ohtsuka, Hitoshi Niwa
Journal: Development
Development (2015) 142 (3): 431–437.
https://doi.org/10.1242/dev.112375
Published: 1 February 2015
View article titled, The differential activation of intracellular signaling pathways confers the permissiveness of embryonic stem cell derivation from different mouse strains
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Includes: Supplementary data
Journal Articles

Small molecule-directed specification of sclerotome-like chondroprogenitors and induction of a somitic chondrogenesis program from embryonic stem cells

Jiangang Zhao, Songhui Li, Suprita Trilok, Makoto Tanaka, Vanta Jokubaitis-Jameson, Bei Wang, Hitoshi Niwa, Naoki Nakayama
Journal: Development
Development (2014) 141 (20): 3848–3858.
https://doi.org/10.1242/dev.105981
Published: 15 October 2014
View article titled, Small molecule-directed specification of sclerotome-like chondroprogenitors and induction of a somitic chondrogenesis program from embryonic stem cells
Open the PDF for Small molecule-directed specification of sclerotome-like chondroprogenitors and induction of a somitic chondrogenesis program from embryonic stem cells in another window
Includes: Supplementary data
Journal Articles

The POU-er of gene nomenclature

Stephen R. Frankenberg, Dale Frank, Richard Harland, Andrew D. Johnson, Jennifer Nichols, Hitoshi Niwa, Hans R. Schöler, Elly Tanaka, Chris Wylie, Joshua M. Brickman
Journal: Development
Development (2014) 141 (15): 2921–2923.
https://doi.org/10.1242/dev.108407
Published: 1 August 2014
View article titled, The POU-er of gene nomenclature
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Journal Articles

Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells

Kazuhiro Murakami, Kimi Araki, Satoshi Ohtsuka, Teruhiko Wakayama, Hitoshi Niwa
Journal: Development
Development (2014) 141 (14): 2913–2917.
https://doi.org/10.1242/dev.114207
Published: 15 July 2014
View article titled, Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells
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Journal Articles

Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst

Gloryn Chia Le Bin, Silvia Muñoz-Descalzo, Agata Kurowski, Harry Leitch, Xinghua Lou, William Mansfield, Charles Etienne-Dumeau, Nils Grabole, Carla Mulas, Hitoshi Niwa, Anna-Katerina Hadjantonakis, Jennifer Nichols
Journal: Development
Development (2014) 141 (5): 1001–1010.
https://doi.org/10.1242/dev.096875
Published: 1 March 2014
View article titled, Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst
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Includes: Supplementary data
Journal Articles

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells

Makiko Iwafuchi-Doi, Kazunari Matsuda, Kazuhiro Murakami, Hitoshi Niwa, Paul J. Tesar, Jun Aruga, Isao Matsuo, Hisato Kondoh
Journal: Development
Development (2012) 139 (24): 4675.
https://doi.org/10.1242/dev.091181
Published: 15 December 2012
View article titled, Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells
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Journal Articles

Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells

Makiko Iwafuchi-Doi, Kazunari Matsuda, Kazuhiro Murakami, Hitoshi Niwa, Paul J. Tesar, Jun Aruga, Isao Matsuo, Hisato Kondoh
Journal: Development
Development (2012) 139 (21): 3926–3937.
https://doi.org/10.1242/dev.085936
Published: 1 November 2012
View article titled, Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells
Open the PDF for Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells in another window
Includes: Supplementary data
Journal Articles

Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells

Kazuhiro Murakami, Kimi Araki, Satoshi Ohtsuka, Teruhiko Wakayama, Hitoshi Niwa
Journal: Development
Development (2011) 138 (2): 197–202.
https://doi.org/10.1242/dev.056606
Published: 15 January 2011
View article titled, Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells
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Includes: Supplementary data
Journal Articles

Identification and characterization of subpopulations in undifferentiated ES cell culture

Yayoi Toyooka, Daisuke Shimosato, Kazuhiro Murakami, Kadue Takahashi, Hitoshi Niwa
Journal: Development
Development (2008) 135 (5): 909–918.
https://doi.org/10.1242/dev.017400
Published: 1 March 2008
View article titled, Identification and characterization of subpopulations in undifferentiated ES cell culture
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Journal Articles

How is pluripotency determined and maintained?

Hitoshi Niwa
Journal: Development
Development (2007) 134 (4): 635–646.
https://doi.org/10.1242/dev.02787
Published: 15 February 2007
View article titled, How is pluripotency determined and maintained?
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Journal Articles

Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures

Koji Shimozaki, Kinichi Nakashima, Hitoshi Niwa, Tetsuya Taga
Journal: Development
Development (2003) 130 (11): 2505–2512.
https://doi.org/10.1242/dev.00476
Published: 1 June 2003
View article titled, Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures
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Includes: Supplementary data