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STEM CELLS AND REGENERATION

Summary: Perturbation of glia with ets-1(RNAi) alters neuronal gene expression, impedes animal movement and impairs nervous system architecture in planarians.

RESEARCH ARTICLES

Summary: The neuronal furin-like proprotein convertase KPC-1 in Caenorhabditis elegans requires catalytic activity to non-autonomously regulate the Menorin adhesion complex from adjacent tissues, thereby providing negative feedback during dendrite development.

Summary: An acytokinetic cell division breaks the initial membrane symmetry in embryonic garland nephrocytes creating PIP2-enriched membrane microdomains suitable for slit diaphragm assembly.

Highlighted Article: Loss of Rasa1 in zebrafish leads to cavernous arteriovenous malformations with venous-specific increased MEK/ERK activity and cell size, and disrupted angiogenesis and blood flow.

Summary: Examination of the migration and morphogenesis of Drosophila visceral muscle precursors reveals how these multinucleated precursors form the stereotypic arrangement of longitudinal gut muscles and identifies Tey as a crucial regulator of this process.

Summary: Dynamic expression of Zbtb16 underlies downregulation of early segmental fgf3 expression in the zebrafish hindbrain, enabling the correct pattern of Fgf signalling at later stages when Fgf20 organizes neurogenesis.

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